CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = M : Mut = L22L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
M22L22LsynCtaTta243022050.90740726586-26588
M22L22LsynctActG24301430.058847726586-26588
M22L22LsynctActT2430600.024691426586-26588
M22L22LsynctActC2430210.0086419826586-26588
M22L22LsynCtATtG243010.00041152326586-26588

Details of the mutation L22L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
M22L22LCtaTta22052430All0.000422
M22L22LctActG1432430All0.000027
M22L22LctActT602430All0.000011
M22L22LctActC212430All0.000004
M22L22LCtATtG12430All0
M22L22LCtaTta16691671AY.40.002598
M22L22LctActG11671AY.40.000002
M22L22LctActC11671AY.40.000002
M22L22LCtaTta7994B.1.1.70.000071
M22L22LctActT994B.1.1.70.000008
M22L22LctActG594B.1.1.70.000004
M22L22LCtATtG194B.1.1.70.000001
M22L22LctActG7586AY.430.000332
M22L22LCtaTta986AY.430.00004
M22L22LctActT286AY.430.000009
M22L22LCtaTta7777B.1.1.2730.52027
M22L22LctActG4346B.1.5250.004866
M22L22LCtaTta246B.1.5250.000226
M22L22LctActT146B.1.5250.000113
M22L22LCtaTta4545AY.420.00181
M22L22LCtaTta3638B.1.617.20.000136
M22L22LctActT138B.1.617.20.000004
M22L22LctActG138B.1.617.20.000004
M22L22LCtaTta2629AY.250.000156
M22L22LctActT329AY.250.000018
M22L22LctActC1217B.1.20.000106
M22L22LCtaTta217B.1.20.000018
M22L22LctActG217B.1.20.000018
M22L22LctActT117B.1.20.000009
M22L22LCtaTta1717C.390.320755
M22L22LCtaTta1116AY.440.000067
M22L22LctActC316AY.440.000018
M22L22LctActT216AY.440.000012
M22L22LCtaTta1214AY.290.000189
M22L22LctActG114AY.290.000016
M22L22LctActT114AY.290.000016
M22L22LCtaTta1313AY.840.005687
M22L22LCtaTta1111AT.10.05641
M22L22LCtaTta1111AY.540.001049
M22L22LCtaTta611B.10.000055
M22L22LctActT411B.10.000037
M22L22LctActG111B.10.000009
M22L22LCtaTta811B.1.3510.000238
M22L22LctActT311B.1.3510.000089
M22L22LCtaTta710AY.200.000272
M22L22LctActT310AY.200.000117
M22L22LCtaTta1010B.1.10.000181
M22L22LCtaTta69AY.850.002563
M22L22LctActT29AY.850.000854
M22L22LctActG19AY.850.000427
M22L22LCtaTta99B.1.1.5190.000357
M22L22LCtaTta99C.130.230769
M22L22LCtaTta46B.1.1770.000053
M22L22LctActT26B.1.1770.000026
M22L22LCtaTta66C.370.000696
M22L22LCtaTta45AY.1020.000106
M22L22LctActG15AY.1020.000027
M22L22LCtaTta45AY.1030.000025
M22L22LctActG15AY.1030.000006
M22L22LctActC35AY.360.000445
M22L22LCtaTta25AY.360.000296
M22L22LctActG35AY.390.000074
M22L22LCtaTta25AY.390.000049
M22L22LctActT24AY.1190.000071
M22L22LCtaTta24AY.1190.000071
M22L22LCtaTta44AY.470.000124
M22L22LCtaTta44B.1.1600.000125
M22L22LctActT44B.1.3200.004981
M22L22LCtaTta34B.1.617.10.000387
M22L22LctActG14B.1.617.10.000129
M22L22LCtaTta44P.10.000063
M22L22LctActT23AY.350.000466
M22L22LCtaTta13AY.350.000233
M22L22LCtaTta23AY.50.000041
M22L22LctActG13AY.50.000021
M22L22LCtaTta33B.1.1.630.001157
M22L22LCtaTta23B.1.177.210.000153
M22L22LctActT13B.1.177.210.000076
M22L22LctActC23B.1.4270.000101
M22L22LCtaTta13B.1.4270.00005
M22L22LCtaTta33B.1.4970.000944
M22L22LCtaTta33B.1.5820.001472
M22L22LCtaTta33B.1.6210.000266
M22L22LctActT33P.1.140.000143
M22L22LCtaTta33P.20.00056
M22L22LCtaTta22AY.1000.000092
M22L22LctActG22AY.260.000057
M22L22LCtaTta22AY.39.10.000079
M22L22LCtaTta22AY.4.20.000043
M22L22LCtaTta22AY.550.001835
M22L22LCtaTta12AY.60.000041
M22L22LctActT12AY.60.000041
M22L22LCtaTta22B.1.1.10.000653
M22L22LctActT22B.1.1.3060.000877
M22L22LCtaTta22B.1.2430.000139
M22L22LCtaTta22B.1.2580.000133
M22L22LctActT22B.1.258.170.000208
M22L22LctActT12B.1.360.000146
M22L22LCtaTta12B.1.360.000146
M22L22LCtaTta22B.1.36.310.003503
M22L22LCtaTta22B.1.4990.002101
M22L22LCtaTta22B.1.5750.000607
M22L22LCtaTta22B.1.5960.000174
M22L22LCtaTta22P.1.10.000635
M22L22LCtaTta22Q.80.00033
M22L22LctActT11AY.1010.00049
M22L22LCtaTta11AY.1070.000466
M22L22LCtaTta11AY.1130.000142
M22L22LCtaTta11AY.1210.000135
M22L22LCtaTta11AY.230.00007
M22L22LCtaTta11AY.30.00001
M22L22LctActG11AY.300.000396
M22L22LCtaTta11AY.370.000316
M22L22LCtaTta11AY.380.000499
M22L22LCtaTta11AY.450.000122
M22L22LCtaTta11AY.460.000104
M22L22LCtaTta11AY.46.60.000072
M22L22LCtaTta11AY.580.000907
M22L22LCtaTta11AY.610.000105
M22L22LCtaTta11AY.620.000436
M22L22LCtaTta11AY.670.000464
M22L22LctActG11AY.750.000056
M22L22LCtaTta11AY.760.004831
M22L22LCtaTta11AY.80.000606
M22L22LCtaTta11AY.99.20.000092
M22L22LCtaTta11B.1.1.1980.001468
M22L22LCtaTta11B.1.1.2070.001182
M22L22LCtaTta11B.1.1.2160.00089
M22L22LctActT11B.1.1.2190.005
M22L22LctActG11B.1.1.2220.000204
M22L22LCtaTta11B.1.1.250.000569
M22L22LCtaTta11B.1.1.3290.003846
M22L22LCtaTta11B.1.1.3700.012658
M22L22LctActT11B.1.1.4200.001006
M22L22LctActT11B.1.1.4320.001266
M22L22LCtaTta11B.1.1.4480.002033
M22L22LCtaTta11B.1.1.460.004367
M22L22LCtaTta11B.1.1.5230.001563
M22L22LctActT11B.1.177.560.000668
M22L22LCtaTta11B.1.177.830.001481
M22L22LctActG11B.1.2340.000132
M22L22LCtaTta11B.1.258.140.00098
M22L22LCtaTta11B.1.3360.002439
M22L22LCtaTta11B.1.3370.005587
M22L22LCtaTta11B.1.4040.001302
M22L22LCtaTta11B.1.416.10.001563
M22L22LctActT11B.1.4290.000024
M22L22LctActT11B.1.5170.000427
M22L22LCtaTta11B.1.5240.001406
M22L22LctActT11B.1.5260.000024
M22L22LCtaTta11B.1.5610.000397
M22L22LCtaTta11B.1.6250.002353
M22L22LCtaTta11B.1.6370.000073
M22L22LCtaTta11C.10.002392
M22L22LCtaTta11C.350.000774
M22L22LCtaTta11C.36.30.000567
M22L22LCtaTta11D.20.000075
M22L22LCtaTta11Q.70.001111
M22L22LCtaTta11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.