CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = M : Mut = L134L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
M134L134LsynCtaTta262619300.73495826922-26924
M134L134LsynctActG26265780.22010726922-26924
M134L134LsynctActT26261120.042650426922-26924
M134L134LsynctActC262660.0022848426922-26924

Details of the mutation L134L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
M134L134LCtaTta19302626All0.000369
M134L134LctActG5782626All0.000111
M134L134LctActT1122626All0.000021
M134L134LctActC62626All0.000001
M134L134LCtaTta9981074B.1.1.70.000893
M134L134LctActG581074B.1.1.70.000052
M134L134LctActT151074B.1.1.70.000013
M134L134LctActC31074B.1.1.70.000003
M134L134LCtaTta463467AY.440.002818
M134L134LctActG4467AY.440.000024
M134L134LCtaTta9699B.1.6210.008498
M134L134LctActG399B.1.6210.000266
M134L134LCtaTta4786AY.40.000073
M134L134LctActG3886AY.40.000059
M134L134LctActT186AY.40.000002
M134L134LctActT7580AY.330.005008
M134L134LctActG380AY.330.0002
M134L134LCtaTta280AY.330.000134
M134L134LCtaTta5461B.1.617.20.000203
M134L134LctActG561B.1.617.20.000019
M134L134LctActT261B.1.617.20.000008
M134L134LctActG5353A.150.84127
M134L134LctActG4949AE.80.023961
M134L134LctActG2547B.10.000229
M134L134LCtaTta2047B.10.000183
M134L134LctActT247B.10.000018
M134L134LctActG4545B.1.1.3060.019728
M134L134LctActG2539AY.250.00015
M134L134LCtaTta1439AY.250.000084
M134L134LCtaTta3333AY.1020.000875
M134L134LctActG3030B.1.2210.002131
M134L134LCtaTta2028AY.430.000089
M134L134LctActG728AY.430.000031
M134L134LctActT128AY.430.000004
M134L134LCtaTta2028B.1.177.210.001529
M134L134LctActG828B.1.177.210.000612
M134L134LctActG1323B.1.20.000114
M134L134LCtaTta623B.1.20.000053
M134L134LctActT423B.1.20.000035
M134L134LctActG1322B.1.1770.000171
M134L134LCtaTta722B.1.1770.000092
M134L134LctActT222B.1.1770.000026
M134L134LctActG1317AY.30.000129
M134L134LCtaTta417AY.30.00004
M134L134LCtaTta1616AY.290.000252
M134L134LctActG1515AY.200.000583
M134L134LctActG1515B.1.177.450.005719
M134L134LCtaTta713P.10.00011
M134L134LctActG613P.10.000095
M134L134LctActG1212B.1.258.160.01964
M134L134LctActG1011AY.9.20.000367
M134L134LCtaTta111AY.9.20.000037
M134L134LCtaTta911B.1.3510.000268
M134L134LctActG211B.1.3510.000059
M134L134LCtaTta710B.1.1.5190.000278
M134L134LctActG310B.1.1.5190.000119
M134L134LCtaTta89AY.1030.00005
M134L134LctActG19AY.1030.000006
M134L134LctActG99AY.1110.001648
M134L134LctActG69B.1.10.000109
M134L134LCtaTta39B.1.10.000054
M134L134LctActG99B.1.177.160.00598
M134L134LCtaTta59Q.80.000825
M134L134LctActT39Q.80.000495
M134L134LctActG19Q.80.000165
M134L134LCtaTta68AY.390.000148
M134L134LctActG28AY.390.000049
M134L134LCtaTta78AY.540.000667
M134L134LctActG18AY.540.000095
M134L134LctActG68P.1.140.000287
M134L134LctActT18P.1.140.000048
M134L134LCtaTta18P.1.140.000048
M134L134LctActG66B.1.1.630.002315
M134L134LctActG66B.1.160.160.005576
M134L134LCtaTta56B.1.5960.000436
M134L134LctActG16B.1.5960.000087
M134L134LCtaTta45B.1.1600.000125
M134L134LctActG15B.1.1600.000031
M134L134LctActG45B.1.5260.000094
M134L134LCtaTta15B.1.5260.000024
M134L134LCtaTta44AY.116.10.001246
M134L134LCtaTta44AY.340.000388
M134L134LCtaTta44AY.420.000161
M134L134LCtaTta44AY.460.000416
M134L134LCtaTta44B.1.2320.002149
M134L134LctActG44B.1.5380.032258
M134L134LCtaTta44B.1.6370.000292
M134L134LCtaTta33AY.1000.000138
M134L134LctActG23AY.1190.000071
M134L134LCtaTta13AY.1190.000035
M134L134LctActG23AY.4.20.000043
M134L134LCtaTta13AY.4.20.000022
M134L134LCtaTta33AY.450.000365
M134L134LctActG23AY.60.000082
M134L134LctActT13AY.60.000041
M134L134LctActG33AY.610.000314
M134L134LctActG33B0.000383
M134L134LCtaTta23B.1.1.2220.000408
M134L134LctActG13B.1.1.2220.000204
M134L134LctActG33B.1.36.180.001261
M134L134LctActG23B.1.4270.000101
M134L134LCtaTta13B.1.4270.00005
M134L134LctActG33B.550.00885
M134L134LCtaTta33P.30.004785
M134L134LctActG33R.10.00027
M134L134LCtaTta22A.23.10.001408
M134L134LctActG22AY.120.20.002571
M134L134LctActT12AY.230.00007
M134L134LctActG12AY.230.00007
M134L134LctActG22AY.260.000057
M134L134LCtaTta22AY.46.60.000144
M134L134LctActG12AY.50.000021
M134L134LctActT12AY.50.000021
M134L134LctActG22AY.590.001059
M134L134LctActG22AY.840.000875
M134L134LctActG22B.1.1.2840.000215
M134L134LctActG22B.1.2410.001623
M134L134LctActG12B.1.2430.00007
M134L134LCtaTta12B.1.2430.00007
M134L134LctActG22B.1.2580.000133
M134L134LctActG22B.1.3110.000549
M134L134LCtaTta22B.1.3690.00057
M134L134LCtaTta22B.1.4290.000047
M134L134LctActG11AE.20.058824
M134L134LctActG11AY.100.00053
M134L134LCtaTta11AY.1060.000335
M134L134LCtaTta11AY.1080.001103
M134L134LCtaTta11AY.1100.000113
M134L134LctActG11AY.1130.000142
M134L134LCtaTta11AY.1160.000287
M134L134LctActG11AY.1180.000063
M134L134LctActG11AY.1200.000037
M134L134LctActC11AY.120.10.000321
M134L134LctActG11AY.140.000088
M134L134LctActG11AY.160.00038
M134L134LctActT11AY.240.000431
M134L134LctActG11AY.4.50.000107
M134L134LctActG11AY.550.000917
M134L134LctActG11AY.690.000187
M134L134LctActG11AY.740.000116
M134L134LCtaTta11AY.90.000068
M134L134LctActG11B.1.1.1210.002427
M134L134LCtaTta11B.1.1.2140.000055
M134L134LctActC11B.1.1.2770.000759
M134L134LCtaTta11B.1.1.2980.000862
M134L134LCtaTta11B.1.1.3110.000358
M134L134LctActG11B.1.1.3930.111111
M134L134LctActG11B.1.1.5260.003546
M134L134LctActG11B.1.1.700.000341
M134L134LctActG11B.1.160.300.002976
M134L134LctActG11B.1.177.520.001757
M134L134LctActT11B.1.177.560.000668
M134L134LctActG11B.1.177.70.000165
M134L134LctActG11B.1.2340.000132
M134L134LCtaTta11B.1.3250.006897
M134L134LCtaTta11B.1.36.170.000494
M134L134LCtaTta11B.1.36.290.000517
M134L134LctActG11B.1.3620.001541
M134L134LCtaTta11B.1.3960.000706
M134L134LCtaTta11B.1.4280.00102
M134L134LCtaTta11B.1.438.10.000107
M134L134LCtaTta11B.1.5610.000397
M134L134LCtaTta11B.1.5800.004065
M134L134LctActG11B.1.617.10.000129
M134L134LCtaTta11B.1.910.002075
M134L134LctActG11B.3.10.001658
M134L134LCtaTta11C.160.00106
M134L134LCtaTta11C.370.000116
M134L134LctActG11P.1.150.000232
M134L134LctActT11Q.10.000126
M134L134LctActC11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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