CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
M | 118 | I118I | syn | atT | atC | 38566 | 38506 | 0.998444 | 26874-26876 | |
M | 118 | I118I | syn | atT | atA | 38566 | 60 | 0.00155577 | 26874-26876 |
Details of the mutation I118I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
M | 118 | I118I | atT | atC | 38506 | 38566 | All | 0.007365 |
M | 118 | I118I | atT | atA | 60 | 38566 | All | 0.000011 |
M | 118 | I118I | atT | atC | 30117 | 30117 | B.1.160 | 0.939278 |
M | 118 | I118I | atT | atC | 1060 | 1060 | B.1.160.16 | 0.98513 |
M | 118 | I118I | atT | atC | 775 | 775 | B.1.160.8 | 0.998711 |
M | 118 | I118I | atT | atC | 586 | 586 | B.1.160.17 | 0.996599 |
M | 118 | I118I | atT | atC | 481 | 481 | B.1.160.7 | 1 |
M | 118 | I118I | atT | atC | 470 | 470 | B.1.160.14 | 0.995763 |
M | 118 | I118I | atT | atC | 412 | 412 | B.1.160.26 | 0.997579 |
M | 118 | I118I | atT | atC | 334 | 334 | B.1.160.28 | 0.976608 |
M | 118 | I118I | atT | atC | 301 | 304 | B.1 | 0.002757 |
M | 118 | I118I | atT | atA | 3 | 304 | B.1 | 0.000027 |
M | 118 | I118I | atT | atC | 237 | 237 | B.1.160.29 | 1 |
M | 118 | I118I | atT | atC | 224 | 230 | B.1.1.7 | 0.000201 |
M | 118 | I118I | atT | atA | 6 | 230 | B.1.1.7 | 0.000005 |
M | 118 | I118I | atT | atC | 226 | 226 | B.1.160.24 | 1 |
M | 118 | I118I | atT | atC | 225 | 225 | B.1.160.33 | 0.995575 |
M | 118 | I118I | atT | atC | 207 | 207 | B.1.160.23 | 1 |
M | 118 | I118I | atT | atC | 202 | 202 | B.1.160.15 | 1 |
M | 118 | I118I | atT | atC | 202 | 202 | B.1.160.30 | 0.60119 |
M | 118 | I118I | atT | atC | 189 | 189 | B.1.160.32 | 0.811159 |
M | 118 | I118I | atT | atC | 174 | 174 | B.1.160.11 | 0.994286 |
M | 118 | I118I | atT | atC | 156 | 156 | B.1.160.12 | 1 |
M | 118 | I118I | atT | atC | 148 | 148 | B.1.160.22 | 1 |
M | 118 | I118I | atT | atC | 137 | 137 | B.1.160.9 | 0.985612 |
M | 118 | I118I | atT | atC | 124 | 124 | B.1.160.31 | 1 |
M | 118 | I118I | atT | atC | 122 | 122 | AB.1 | 1 |
M | 118 | I118I | atT | atC | 118 | 118 | B.1.160.10 | 0.951613 |
M | 118 | I118I | atT | atC | 106 | 106 | B.1.160.18 | 0.773723 |
M | 118 | I118I | atT | atC | 90 | 90 | B.1.160.25 | 1 |
M | 118 | I118I | atT | atC | 79 | 80 | B.1.177 | 0.00104 |
M | 118 | I118I | atT | atA | 1 | 80 | B.1.177 | 0.000013 |
M | 118 | I118I | atT | atC | 79 | 79 | B.1.160.20 | 0.705357 |
M | 118 | I118I | atT | atC | 66 | 66 | B.1.1 | 0.001197 |
M | 118 | I118I | atT | atC | 65 | 65 | B.1.160.27 | 0.984848 |
M | 118 | I118I | atT | atC | 61 | 61 | B.1.36.23 | 1 |
M | 118 | I118I | atT | atC | 60 | 60 | B.1.221 | 0.004262 |
M | 118 | I118I | atT | atC | 51 | 51 | AY.25 | 0.000307 |
M | 118 | I118I | atT | atC | 49 | 49 | B.1.160.21 | 1 |
M | 118 | I118I | atT | atC | 36 | 36 | B.1.160.13 | 1 |
M | 118 | I118I | atT | atC | 35 | 35 | B.1.177.31 | 0.402299 |
M | 118 | I118I | atT | atC | 34 | 34 | AY.26 | 0.000963 |
M | 118 | I118I | atT | atC | 34 | 34 | B.1.351.2 | 0.010287 |
M | 118 | I118I | atT | atC | 32 | 32 | B.1.177.44 | 0.016606 |
M | 118 | I118I | atT | atA | 29 | 29 | B.1.177.60 | 0.006335 |
M | 118 | I118I | atT | atC | 28 | 28 | B.1.160.19 | 1 |
M | 118 | I118I | atT | atC | 21 | 27 | AY.4 | 0.000033 |
M | 118 | I118I | atT | atA | 6 | 27 | AY.4 | 0.000009 |
M | 118 | I118I | atT | atC | 26 | 26 | B.1.1.445 | 0.962963 |
M | 118 | I118I | atT | atC | 24 | 24 | B.1.1.39 | 0.012232 |
M | 118 | I118I | atT | atC | 20 | 20 | B.1.258.11 | 0.007927 |
M | 118 | I118I | atT | atC | 15 | 15 | B.1.260 | 0.050167 |
M | 118 | I118I | atT | atC | 10 | 14 | B.1.2 | 0.000088 |
M | 118 | I118I | atT | atA | 4 | 14 | B.1.2 | 0.000035 |
M | 118 | I118I | atT | atC | 13 | 13 | AY.46.6 | 0.000939 |
M | 118 | I118I | atT | atC | 13 | 13 | B | 0.001662 |
M | 118 | I118I | atT | atC | 13 | 13 | B.1.177.43 | 0.019202 |
M | 118 | I118I | atT | atC | 11 | 11 | B.1.177.73 | 0.006229 |
M | 118 | I118I | atT | atC | 10 | 10 | B.1.36.1 | 0.011403 |
M | 118 | I118I | atT | atC | 8 | 8 | B.1.258 | 0.000532 |
M | 118 | I118I | atT | atC | 6 | 6 | AY.34 | 0.000582 |
M | 118 | I118I | atT | atC | 6 | 6 | B.1.177.81 | 0.001136 |
M | 118 | I118I | atT | atC | 6 | 6 | B.1.462 | 0.043478 |
M | 118 | I118I | atT | atC | 6 | 6 | B.1.473 | 0.115385 |
M | 118 | I118I | atT | atC | 6 | 6 | B.1.509 | 0.005195 |
M | 118 | I118I | atT | atC | 5 | 6 | B.1.617.2 | 0.000019 |
M | 118 | I118I | atT | atA | 1 | 6 | B.1.617.2 | 0.000004 |
M | 118 | I118I | atT | atC | 6 | 6 | P.1 | 0.000095 |
M | 118 | I118I | atT | atC | 5 | 5 | B.1.1.70 | 0.001705 |
M | 118 | I118I | atT | atC | 5 | 5 | B.1.236 | 0.010267 |
M | 118 | I118I | atT | atC | 5 | 5 | B.1.533 | 0.048077 |
M | 118 | I118I | atT | atC | 3 | 4 | AY.3 | 0.00003 |
M | 118 | I118I | atT | atA | 1 | 4 | AY.3 | 0.00001 |
M | 118 | I118I | atT | atC | 4 | 4 | AY.5 | 0.000083 |
M | 118 | I118I | atT | atC | 4 | 4 | B.1.36 | 0.000584 |
M | 118 | I118I | atT | atC | 4 | 4 | B.1.465 | 0.015209 |
M | 118 | I118I | atT | atC | 4 | 4 | B.1.561 | 0.001588 |
M | 118 | I118I | atT | atC | 3 | 3 | A | 0.001161 |
M | 118 | I118I | atT | atC | 3 | 3 | AY.103 | 0.000019 |
M | 118 | I118I | atT | atC | 2 | 3 | AY.3.1 | 0.000171 |
M | 118 | I118I | atT | atA | 1 | 3 | AY.3.1 | 0.000085 |
M | 118 | I118I | atT | atC | 3 | 3 | B.1.1.1 | 0.00098 |
M | 118 | I118I | atT | atC | 3 | 3 | B.1.177.23 | 0.009709 |
M | 118 | I118I | atT | atC | 3 | 3 | B.1.177.75 | 0.003122 |
M | 118 | I118I | atT | atC | 3 | 3 | B.1.222 | 0.005076 |
M | 118 | I118I | atT | atC | 3 | 3 | B.1.351 | 0.000089 |
M | 118 | I118I | atT | atC | 3 | 3 | B.1.36.29 | 0.001552 |
M | 118 | I118I | atT | atC | 2 | 3 | B.1.596 | 0.000174 |
M | 118 | I118I | atT | atA | 1 | 3 | B.1.596 | 0.000087 |
M | 118 | I118I | atT | atC | 3 | 3 | B.1.609 | 0.001438 |
M | 118 | I118I | atT | atA | 1 | 2 | AY.100 | 0.000046 |
M | 118 | I118I | atT | atC | 1 | 2 | AY.100 | 0.000046 |
M | 118 | I118I | atT | atC | 2 | 2 | AY.114 | 0.000462 |
M | 118 | I118I | atT | atC | 1 | 2 | AY.43 | 0.000004 |
M | 118 | I118I | atT | atA | 1 | 2 | AY.43 | 0.000004 |
M | 118 | I118I | atT | atC | 2 | 2 | AY.47 | 0.000062 |
M | 118 | I118I | atT | atC | 2 | 2 | AY.9 | 0.000135 |
M | 118 | I118I | atT | atC | 2 | 2 | B.1.1.222 | 0.000408 |
M | 118 | I118I | atT | atC | 2 | 2 | B.1.1.37 | 0.000386 |
M | 118 | I118I | atT | atC | 2 | 2 | B.1.1.398 | 0.006452 |
M | 118 | I118I | atT | atC | 2 | 2 | B.1.1.519 | 0.000079 |
M | 118 | I118I | atT | atC | 2 | 2 | B.1.177.12 | 0.000303 |
M | 118 | I118I | atT | atC | 1 | 2 | B.1.177.21 | 0.000076 |
M | 118 | I118I | atT | atA | 1 | 2 | B.1.177.21 | 0.000076 |
M | 118 | I118I | atT | atC | 2 | 2 | B.1.258.17 | 0.000208 |
M | 118 | I118I | atT | atC | 2 | 2 | B.1.36.8 | 0.002 |
M | 118 | I118I | atT | atC | 2 | 2 | B.1.378 | 0.013699 |
M | 118 | I118I | atT | atC | 2 | 2 | B.1.409 | 0.001563 |
M | 118 | I118I | atT | atC | 2 | 2 | B.1.416.1 | 0.003125 |
M | 118 | I118I | atT | atA | 2 | 2 | C.37 | 0.000232 |
M | 118 | I118I | atT | atC | 2 | 2 | R.1 | 0.00018 |
M | 118 | I118I | atT | atC | 1 | 1 | A.2 | 0.000662 |
M | 118 | I118I | atT | atC | 1 | 1 | AF.1 | 0.037037 |
M | 118 | I118I | atT | atC | 1 | 1 | AN.1 | 0.02 |
M | 118 | I118I | atT | atC | 1 | 1 | AY.102 | 0.000027 |
M | 118 | I118I | atT | atC | 1 | 1 | AY.116 | 0.000287 |
M | 118 | I118I | atT | atC | 1 | 1 | AY.120 | 0.000037 |
M | 118 | I118I | atT | atC | 1 | 1 | AY.23 | 0.00007 |
M | 118 | I118I | atT | atC | 1 | 1 | AY.29 | 0.000016 |
M | 118 | I118I | atT | atC | 1 | 1 | AY.36 | 0.000148 |
M | 118 | I118I | atT | atC | 1 | 1 | AY.39 | 0.000025 |
M | 118 | I118I | atT | atC | 1 | 1 | AY.45 | 0.000122 |
M | 118 | I118I | atT | atC | 1 | 1 | AY.61 | 0.000105 |
M | 118 | I118I | atT | atC | 1 | 1 | AY.69 | 0.000187 |
M | 118 | I118I | atT | atC | 1 | 1 | AY.75 | 0.000056 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.1.153 | 0.001095 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.1.161 | 0.003534 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.1.170 | 0.001247 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.1.236 | 0.006897 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.1.269 | 0.001353 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.1.277 | 0.000759 |
M | 118 | I118I | atT | atA | 1 | 1 | B.1.1.317 | 0.000412 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.1.343 | 0.020833 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.1.385 | 0.004464 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.1.409 | 0.002833 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.1.433 | 0.001425 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.1.47 | 0.005348 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.1.50 | 0.000679 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.124 | 0.007812 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.139 | 0.000733 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.157 | 0.002985 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.177.17 | 0.000821 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.177.45 | 0.000381 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.177.8 | 0.000752 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.177.87 | 0.000728 |
M | 118 | I118I | atT | atA | 1 | 1 | B.1.240 | 0.000216 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.268 | 0.010417 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.326 | 0.007576 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.36.35 | 0.002604 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.367 | 0.000792 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.416 | 0.001269 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.428 | 0.00102 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.438.1 | 0.000107 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.460 | 0.017857 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.468 | 0.005714 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.567 | 0.003333 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.577 | 0.000687 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.581 | 0.009434 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.590 | 0.004545 |
M | 118 | I118I | atT | atC | 1 | 1 | B.1.600 | 0.005848 |
M | 118 | I118I | atT | atC | 1 | 1 | B.23 | 0.002924 |
M | 118 | I118I | atT | atC | 1 | 1 | B.40 | 0.000364 |
M | 118 | I118I | atT | atC | 1 | 1 | B.55 | 0.00295 |
M | 118 | I118I | atT | atC | 1 | 1 | D.2 | 0.000075 |
M | 118 | I118I | atT | atC | 1 | 1 | P.1.15 | 0.000232 |
M | 118 | I118I | atT | atC | 1 | 1 | Z.1 | 0.00289 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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