CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = M : Mut = D215G

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
M	215	D215G		nonsyn	gAc	gGc	37	35	0.945946	27165-27167
M	215	D215G		nonsyn	gAC	gGA	37	2	0.0540541	27165-27167

Details of the mutation D215G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
M	215	D215G	gAc	gGc	35	37	All	0.000007
M	215	D215G	gAC	gGA	2	37	All	0
M	215	D215G	gAc	gGc	7	7	AY.43	0.000031
M	215	D215G	gAc	gGc	6	6	AY.98	0.000474
M	215	D215G	gAc	gGc	5	5	B.1.617.2	0.000019
M	215	D215G	gAc	gGc	3	3	AY.4	0.000005
M	215	D215G	gAc	gGc	3	3	AY.44	0.000018
M	215	D215G	gAc	gGc	1	2		0.055556
M	215	D215G	gAC	gGA	1	2		0.055556
M	215	D215G	gAc	gGc	2	2	B.1.1.7	0.000002
M	215	D215G	gAc	gGc	1	1	AY.3	0.00001
M	215	D215G	gAc	gGc	1	1	AY.46	0.000104
M	215	D215G	gAC	gGA	1	1	B	0.000128
M	215	D215G	gAc	gGc	1	1	B.1.177.21	0.000076
M	215	D215G	gAc	gGc	1	1	B.1.2	0.000009
M	215	D215G	gAc	gGc	1	1	B.1.351	0.00003
M	215	D215G	gAc	gGc	1	1	B.1.400	0.000429
M	215	D215G	gAc	gGc	1	1	B.1.470	0.001404
M	215	D215G	gAc	gGc	1	1	P.2	0.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.