CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = M : Mut = D215D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
M	215	D215D		syn	gaC	gaT	1343	1343	1	27165-27167

Details of the mutation D215D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
M	215	D215D	gaC	gaT	1343	1343	All	0.000257
M	215	D215D	gaC	gaT	175	175	AY.103	0.001087
M	215	D215D	gaC	gaT	169	169	AY.23	0.011788
M	215	D215D	gaC	gaT	156	156	AY.43	0.000691
M	215	D215D	gaC	gaT	142	142	B.1.1.7	0.000127
M	215	D215D	gaC	gaT	123	123	B.1.617.2	0.000463
M	215	D215D	gaC	gaT	76	76	AY.4	0.000118
M	215	D215D	gaC	gaT	45	45	AY.25	0.000271
M	215	D215D	gaC	gaT	42	42	AY.3	0.000418
M	215	D215D	gaC	gaT	40	40	AY.44	0.000243
M	215	D215D	gaC	gaT	38	38	B.1.160	0.001185
M	215	D215D	gaC	gaT	35	35	AY.42	0.001408
M	215	D215D	gaC	gaT	22	22	B.1.2	0.000194
M	215	D215D	gaC	gaT	17	17	AY.20	0.000661
M	215	D215D	gaC	gaT	12	12	B.1	0.00011
M	215	D215D	gaC	gaT	9	9	AY.39	0.000222
M	215	D215D	gaC	gaT	9	9	AY.39.1	0.000357
M	215	D215D	gaC	gaT	9	9	B.1.1	0.000163
M	215	D215D	gaC	gaT	8	8	AY.33	0.000534
M	215	D215D	gaC	gaT	8	8	AY.98.1	0.000387
M	215	D215D	gaC	gaT	7	7	AY.102	0.000186
M	215	D215D	gaC	gaT	7	7	AY.4.2.1	0.001043
M	215	D215D	gaC	gaT	7	7	AY.41	0.002058
M	215	D215D	gaC	gaT	6	6	AY.100	0.000276
M	215	D215D	gaC	gaT	6	6	B.1.429	0.000141
M	215	D215D	gaC	gaT	5	5	AY.13	0.000805
M	215	D215D	gaC	gaT	5	5	AY.4.2	0.000108
M	215	D215D	gaC	gaT	5	5	B.1.619	0.004355
M	215	D215D	gaC	gaT	5	5	B.1.637	0.000365
M	215	D215D	gaC	gaT	4	4	AY.120	0.000149
M	215	D215D	gaC	gaT	4	4	AY.47	0.000124
M	215	D215D	gaC	gaT	4	4	AY.61	0.000419
M	215	D215D	gaC	gaT	4	4	B.1.177	0.000053
M	215	D215D	gaC	gaT	4	4	B.1.391	0.00451
M	215	D215D	gaC	gaT	4	4	B.1.525	0.000453
M	215	D215D	gaC	gaT	4	4	B.1.526	0.000094
M	215	D215D	gaC	gaT	4	4	Q.4	0.001819
M	215	D215D	gaC	gaT	3	3	AY.26	0.000085
M	215	D215D	gaC	gaT	3	3	AY.46	0.000312
M	215	D215D	gaC	gaT	3	3	AY.5	0.000062
M	215	D215D	gaC	gaT	3	3	AY.9.1	0.000251
M	215	D215D	gaC	gaT	3	3	B.1.243	0.000209
M	215	D215D	gaC	gaT	3	3	B.1.258.17	0.000312
M	215	D215D	gaC	gaT	3	3	B.1.351	0.000089
M	215	D215D	gaC	gaT	3	3	P.1	0.000047
M	215	D215D	gaC	gaT	2	2	A.2	0.001324
M	215	D215D	gaC	gaT	2	2	AY.117	0.000169
M	215	D215D	gaC	gaT	2	2	AY.119	0.000071
M	215	D215D	gaC	gaT	2	2	AY.34.1	0.00102
M	215	D215D	gaC	gaT	2	2	AY.5.4	0.000553
M	215	D215D	gaC	gaT	2	2	AY.75	0.000112
M	215	D215D	gaC	gaT	2	2	AY.98	0.000158
M	215	D215D	gaC	gaT	2	2	B	0.000256
M	215	D215D	gaC	gaT	2	2	B.1.1.39	0.001019
M	215	D215D	gaC	gaT	2	2	B.1.1.519	0.000079
M	215	D215D	gaC	gaT	2	2	B.1.22	0.002635
M	215	D215D	gaC	gaT	2	2	B.1.221	0.000142
M	215	D215D	gaC	gaT	2	2	B.1.36	0.000292
M	215	D215D	gaC	gaT	2	2	B.1.438.1	0.000215
M	215	D215D	gaC	gaT	2	2	B.1.459	0.008163
M	215	D215D	gaC	gaT	2	2	B.1.532	0.012422
M	215	D215D	gaC	gaT	2	2	B.6.6	0.001778
M	215	D215D	gaC	gaT	2	2	P.1.6	0.003891
M	215	D215D	gaC	gaT	2	2	Q.3	0.00029
M	215	D215D	gaC	gaT	1	1	A.1	0.000282
M	215	D215D	gaC	gaT	1	1	A.2.5	0.000499
M	215	D215D	gaC	gaT	1	1	AE.8	0.000489
M	215	D215D	gaC	gaT	1	1	AY.106	0.000335
M	215	D215D	gaC	gaT	1	1	AY.110	0.000113
M	215	D215D	gaC	gaT	1	1	AY.114	0.000231
M	215	D215D	gaC	gaT	1	1	AY.120.2	0.001285
M	215	D215D	gaC	gaT	1	1	AY.120.2.1	0.000498
M	215	D215D	gaC	gaT	1	1	AY.16	0.00038
M	215	D215D	gaC	gaT	1	1	AY.2	0.000356
M	215	D215D	gaC	gaT	1	1	AY.23.1	0.000417
M	215	D215D	gaC	gaT	1	1	AY.29	0.000016
M	215	D215D	gaC	gaT	1	1	AY.34	0.000097
M	215	D215D	gaC	gaT	1	1	AY.37	0.000316
M	215	D215D	gaC	gaT	1	1	AY.40	0.000964
M	215	D215D	gaC	gaT	1	1	AY.45	0.000122
M	215	D215D	gaC	gaT	1	1	AY.46.6	0.000072
M	215	D215D	gaC	gaT	1	1	AY.48	0.000465
M	215	D215D	gaC	gaT	1	1	AY.57	0.000656
M	215	D215D	gaC	gaT	1	1	AY.6	0.000041
M	215	D215D	gaC	gaT	1	1	AY.62	0.000436
M	215	D215D	gaC	gaT	1	1	AY.63	0.000387
M	215	D215D	gaC	gaT	1	1	AY.70	0.000209
M	215	D215D	gaC	gaT	1	1	AY.74	0.000116
M	215	D215D	gaC	gaT	1	1	AY.75.1	0.00018
M	215	D215D	gaC	gaT	1	1	AY.76	0.004831
M	215	D215D	gaC	gaT	1	1	AY.88	0.000884
M	215	D215D	gaC	gaT	1	1	AY.91.1	0.004065
M	215	D215D	gaC	gaT	1	1	AZ.2	0.000821
M	215	D215D	gaC	gaT	1	1	B.1.1.214	0.000055
M	215	D215D	gaC	gaT	1	1	B.1.1.284	0.000107
M	215	D215D	gaC	gaT	1	1	B.1.1.37	0.000193
M	215	D215D	gaC	gaT	1	1	B.1.1.50	0.000679
M	215	D215D	gaC	gaT	1	1	B.1.149	0.003425
M	215	D215D	gaC	gaT	1	1	B.1.177.81	0.000189
M	215	D215D	gaC	gaT	1	1	B.1.258	0.000067
M	215	D215D	gaC	gaT	1	1	B.1.258.12	0.007874
M	215	D215D	gaC	gaT	1	1	B.1.258.3	0.001675
M	215	D215D	gaC	gaT	1	1	B.1.279	0.000514
M	215	D215D	gaC	gaT	1	1	B.1.284	0.013158
M	215	D215D	gaC	gaT	1	1	B.1.311	0.000275
M	215	D215D	gaC	gaT	1	1	B.1.36.36	0.000602
M	215	D215D	gaC	gaT	1	1	B.1.369	0.000285
M	215	D215D	gaC	gaT	1	1	B.1.389	0.001002
M	215	D215D	gaC	gaT	1	1	B.1.400	0.000429
M	215	D215D	gaC	gaT	1	1	B.1.427	0.00005
M	215	D215D	gaC	gaT	1	1	B.1.451	0.008197
M	215	D215D	gaC	gaT	1	1	B.1.549	0.007194
M	215	D215D	gaC	gaT	1	1	B.1.575	0.000303
M	215	D215D	gaC	gaT	1	1	B.1.595	0.000261
M	215	D215D	gaC	gaT	1	1	B.1.596	0.000087
M	215	D215D	gaC	gaT	1	1	B.1.621	0.000089
M	215	D215D	gaC	gaT	1	1	B.1.9.5	0.005682
M	215	D215D	gaC	gaT	1	1	B.40	0.000364
M	215	D215D	gaC	gaT	1	1	B.6	0.00091
M	215	D215D	gaC	gaT	1	1	C.37	0.000116
M	215	D215D	gaC	gaT	1	1	C.37.1	0.002618
M	215	D215D	gaC	gaT	1	1	P.1.12	0.000484
M	215	D215D	gaC	gaT	1	1	P.1.7	0.000319
M	215	D215D	gaC	gaT	1	1	Q.8	0.000165
M	215	D215D	gaC	gaT	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.