CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = M : Mut = A2A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
M2A2AsyngcAgcT404028170.69727726526-26528
M2A2AsyngcAgcG404011640.28811926526-26528
M2A2AsyngcAgcC4040590.01460426526-26528

Details of the mutation A2A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
M2A2AgcAgcT28174040All0.000539
M2A2AgcAgcG11644040All0.000223
M2A2AgcAgcC594040All0.000011
M2A2AgcAgcG9861228B.1.1.70.000883
M2A2AgcAgcT2371228B.1.1.70.000212
M2A2AgcAgcC51228B.1.1.70.000004
M2A2AgcAgcT926929AY.50.019121
M2A2AgcAgcG3929AY.50.000062
M2A2AgcAgcT195250B.1.617.20.000734
M2A2AgcAgcG52250B.1.617.20.000196
M2A2AgcAgcC3250B.1.617.20.000011
M2A2AgcAgcT222228AY.40.000346
M2A2AgcAgcG6228AY.40.000009
M2A2AgcAgcT145150AY.430.000642
M2A2AgcAgcG5150AY.430.000022
M2A2AgcAgcT135136B.1.1770.001778
M2A2AgcAgcG1136B.1.1770.000013
M2A2AgcAgcT113113B.1.2430.007863
M2A2AgcAgcT6565AY.1000.00299
M2A2AgcAgcT5861AY.250.000349
M2A2AgcAgcG261AY.250.000012
M2A2AgcAgcC161AY.250.000006
M2A2AgcAgcT5858B.1.2340.007653
M2A2AgcAgcT5051AY.440.000304
M2A2AgcAgcC151AY.440.000006
M2A2AgcAgcT2949AY.1030.00018
M2A2AgcAgcC1549AY.1030.000093
M2A2AgcAgcG549AY.1030.000031
M2A2AgcAgcG3944Q.80.006431
M2A2AgcAgcT544Q.80.000825
M2A2AgcAgcT3237B.10.000293
M2A2AgcAgcG337B.10.000027
M2A2AgcAgcC237B.10.000018
M2A2AgcAgcT3636AY.1210.004871
M2A2AgcAgcT3234B.1.20.000282
M2A2AgcAgcG234B.1.20.000018
M2A2AgcAgcT3233AY.200.001244
M2A2AgcAgcG133AY.200.000039
M2A2AgcAgcT3030AY.5.40.008301
M2A2AgcAgcT2626B.1.3510.000773
M2A2AgcAgcT2326B.1.5260.000541
M2A2AgcAgcG326B.1.5260.000071
M2A2AgcAgcT2525AY.220.052301
M2A2AgcAgcT2525B.1.1.5190.000993
M2A2AgcAgcT2121AY.1190.000741
M2A2AgcAgcT1618AY.230.001116
M2A2AgcAgcG218AY.230.000139
M2A2AgcAgcT1517B.1.10.000272
M2A2AgcAgcG217B.1.10.000036
M2A2AgcAgcT916P.1.10.002859
M2A2AgcAgcG616P.1.10.001906
M2A2AgcAgcC116P.1.10.000318
M2A2AgcAgcT1414B.1.1.4320.017722
M2A2AgcAgcT1313AY.260.000368
M2A2AgcAgcT913AY.30.00009
M2A2AgcAgcC313AY.30.00003
M2A2AgcAgcG113AY.30.00001
M2A2AgcAgcT1313P.10.000205
M2A2AgcAgcT1010AY.1020.000265
M2A2AgcAgcT1010AY.360.001482
M2A2AgcAgcT1010B.1.1.470.053476
M2A2AgcAgcT89C.370.000929
M2A2AgcAgcG19C.370.000116
M2A2AgcAgcT78AY.390.000173
M2A2AgcAgcG18AY.390.000025
M2A2AgcAgcC68AY.46.60.000433
M2A2AgcAgcG28AY.46.60.000144
M2A2AgcAgcC88B.1.4000.003432
M2A2AgcAgcT57AY.1170.000423
M2A2AgcAgcG27AY.1170.000169
M2A2AgcAgcT67AY.420.000241
M2A2AgcAgcC17AY.420.00004
M2A2AgcAgcT77AY.780.010786
M2A2AgcAgcT47AY.9.10.000335
M2A2AgcAgcG37AY.9.10.000251
M2A2AgcAgcC47B.1.6370.000292
M2A2AgcAgcT27B.1.6370.000146
M2A2AgcAgcG17B.1.6370.000073
M2A2AgcAgcT66B.1.177.540.003639
M2A2AgcAgcG66B.1.5170.002562
M2A2AgcAgcT55AY.470.000156
M2A2AgcAgcT55B.1.1.2160.004452
M2A2AgcAgcT55B.1.177.330.008224
M2A2AgcAgcC35B.1.4290.000071
M2A2AgcAgcG25B.1.4290.000047
M2A2AgcAgcT34AY.39.10.000119
M2A2AgcAgcG14AY.39.10.00004
M2A2AgcAgcT44AY.4.20.000087
M2A2AgcAgcG34AY.540.000286
M2A2AgcAgcT14AY.540.000095
M2A2AgcAgcG34AY.90.000203
M2A2AgcAgcT14AY.90.000068
M2A2AgcAgcT44B.1.177.210.000306
M2A2AgcAgcT44B.1.6200.003784
M2A2AgcAgcT33A.280.007937
M2A2AgcAgcT33AY.290.000047
M2A2AgcAgcT33AY.460.000312
M2A2AgcAgcT33B.1.1.3110.001074
M2A2AgcAgcT33B.1.575.10.007317
M2A2AgcAgcT33R.10.00027
M2A2AgcAgcT22AD.20.000438
M2A2AgcAgcT22AY.1080.002205
M2A2AgcAgcC22AY.1140.000462
M2A2AgcAgcT22AY.160.000759
M2A2AgcAgcT22AY.23.10.000835
M2A2AgcAgcT22AY.450.000243
M2A2AgcAgcT22AY.510.001818
M2A2AgcAgcT22AY.550.001835
M2A2AgcAgcT22AY.610.00021
M2A2AgcAgcT22AY.750.000112
M2A2AgcAgcC12AY.840.000437
M2A2AgcAgcT12AY.840.000437
M2A2AgcAgcG12B0.000128
M2A2AgcAgcT12B0.000128
M2A2AgcAgcT22B.1.1.2440.030769
M2A2AgcAgcG22B.1.1.3510.005587
M2A2AgcAgcG12B.1.1.370.000193
M2A2AgcAgcT12B.1.1.370.000193
M2A2AgcAgcT22B.1.1.4160.00181
M2A2AgcAgcT22B.1.1.4200.002012
M2A2AgcAgcT22B.1.1600.000062
M2A2AgcAgcT22B.1.2230.005556
M2A2AgcAgcG22B.1.258.30.00335
M2A2AgcAgcT22B.1.4090.001563
M2A2AgcAgcT22B.1.4270.000101
M2A2AgcAgcT22B.1.4280.002041
M2A2AgcAgcT22B.1.4330.00639
M2A2AgcAgcT22B.1.617.10.000258
M2A2AgcAgcG110.055556
M2A2AgcAgcG11A.2.50.000499
M2A2AgcAgcT11A.210.00277
M2A2AgcAgcT11AU.20.002421
M2A2AgcAgcT11AY.1010.00049
M2A2AgcAgcT11AY.1060.000335
M2A2AgcAgcG11AY.1110.000183
M2A2AgcAgcT11AY.120.000316
M2A2AgcAgcT11AY.1200.000037
M2A2AgcAgcG11AY.120.10.000321
M2A2AgcAgcT11AY.270.000065
M2A2AgcAgcG11AY.280.00189
M2A2AgcAgcT11AY.3.10.000085
M2A2AgcAgcG11AY.330.000067
M2A2AgcAgcT11AY.4.2.10.000149
M2A2AgcAgcT11AY.410.000294
M2A2AgcAgcT11AY.46.10.001027
M2A2AgcAgcG11AY.480.000465
M2A2AgcAgcT11AY.590.00053
M2A2AgcAgcT11AY.60.000041
M2A2AgcAgcT11AY.630.000387
M2A2AgcAgcT11AY.70.000196
M2A2AgcAgcT11AY.740.000116
M2A2AgcAgcC11AY.75.10.00018
M2A2AgcAgcT11AY.810.001992
M2A2AgcAgcT11AY.98.10.000048
M2A2AgcAgcG11B.1.1.250.000569
M2A2AgcAgcG11B.1.1.3060.000438
M2A2AgcAgcG11B.1.1.3120.001912
M2A2AgcAgcT11B.1.1.3260.001761
M2A2AgcAgcT11B.1.1.3370.003597
M2A2AgcAgcT11B.1.1.3690.000446
M2A2AgcAgcT11B.1.1.3980.003226
M2A2AgcAgcT11B.1.1.4300.041667
M2A2AgcAgcC11B.1.1.630.000386
M2A2AgcAgcT11B.1.177.450.000381
M2A2AgcAgcT11B.1.177.550.002331
M2A2AgcAgcT11B.1.177.730.000566
M2A2AgcAgcT11B.1.177.860.000183
M2A2AgcAgcT11B.1.2370.004975
M2A2AgcAgcT11B.1.2580.000067
M2A2AgcAgcT11B.1.3110.000275
M2A2AgcAgcT11B.1.351.20.000303
M2A2AgcAgcT11B.1.36.10.00114
M2A2AgcAgcT11B.1.3970.004854
M2A2AgcAgcT11B.1.4040.001302
M2A2AgcAgcT11B.1.440.008333
M2A2AgcAgcT11B.1.4590.004082
M2A2AgcAgcT11B.1.4630.008065
M2A2AgcAgcT11B.1.596.10.009346
M2A2AgcAgcC11B.1.6210.000089
M2A2AgcAgcG11B.1.6300.005236
M2A2AgcAgcG11B.40.002208
M2A2AgcAgcT11B.4.80.071429
M2A2AgcAgcT11B.60.00091
M2A2AgcAgcG11C.350.000774
M2A2AgcAgcT11P.1.150.000232
M2A2AgcAgcT11P.20.000187
M2A2AgcAgcG11W.40.001351

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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