CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
M | 93 | L93L | syn | ctC | ctG | 195375 | 169074 | 0.865382 | 26799-26801 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
M | 93 | L93L | ctC | ctG | 169074 | 195375 | All | 0.032337 |
M | 93 | L93L | ctC | ctG | 75046 | 75226 | B.1.177 | 0.988175 |
M | 93 | L93L | ctC | ctG | 12567 | 12570 | B.1.177.21 | 0.961 |
M | 93 | L93L | ctC | ctG | 6575 | 6576 | B.1.177.12 | 0.997421 |
M | 93 | L93L | ctC | ctG | 5973 | 5979 | B.1.177.7 | 0.984669 |
M | 93 | L93L | ctC | ctG | 20 | 5376 | B.1.177.86 | 0.003669 |
M | 93 | L93L | ctC | ctG | 5273 | 5274 | B.1.177.81 | 0.998296 |
M | 93 | L93L | ctC | ctG | 4730 | 4736 | B.1.177.4 | 0.998312 |
M | 93 | L93L | ctC | ctG | 4572 | 4572 | B.1.177.60 | 0.998689 |
M | 93 | L93L | ctC | ctG | 3556 | 3557 | B.1.177.57 | 0.999157 |
M | 93 | L93L | ctC | ctG | 108 | 3520 | B.1.1.7 | 0.000097 |
M | 93 | L93L | ctC | ctG | 2619 | 2619 | B.1.177.45 | 0.998475 |
M | 93 | L93L | ctC | ctG | 2081 | 2092 | B.1.177.82 | 0.993317 |
M | 93 | L93L | ctC | ctG | 2 | 1993 | AY.4 | 0.000003 |
M | 93 | L93L | ctC | ctG | 1873 | 1875 | B.1.177.44 | 0.971977 |
M | 93 | L93L | ctC | ctG | 1093 | 1676 | B.1 | 0.010011 |
M | 93 | L93L | ctC | ctG | 1646 | 1646 | B.1.177.54 | 0.998181 |
M | 93 | L93L | ctC | ctG | 1579 | 1580 | B.1.177.15 | 0.996215 |
M | 93 | L93L | ctC | ctG | 1505 | 1505 | B.1.177.16 | 1 |
M | 93 | L93L | ctC | ctG | 1503 | 1503 | B.1.177.65 | 1 |
M | 93 | L93L | ctC | ctG | 1498 | 1498 | B.1.177.56 | 1 |
M | 93 | L93L | ctC | ctG | 1446 | 1446 | B.1.177.35 | 0.999309 |
M | 93 | L93L | ctC | ctG | 1374 | 1375 | B.1.177.77 | 0.997821 |
M | 93 | L93L | ctC | ctG | 1373 | 1373 | B.1.177.87 | 0.999272 |
M | 93 | L93L | ctC | ctG | 1329 | 1329 | B.1.177.8 | 1 |
M | 93 | L93L | ctC | ctG | 1279 | 1283 | B.1.177.73 | 0.724236 |
M | 93 | L93L | ctC | ctG | 1209 | 1210 | B.1.177.17 | 0.992611 |
M | 93 | L93L | ctC | ctG | 1139 | 1139 | B.1.177.10 | 1 |
M | 93 | L93L | ctC | ctG | 1118 | 1118 | B.1.177.42 | 1 |
M | 93 | L93L | ctC | ctG | 1089 | 1089 | B.1.177.46 | 1 |
M | 93 | L93L | ctC | ctG | 992 | 994 | B.1.177.6 | 0.96875 |
M | 93 | L93L | ctC | ctG | 955 | 955 | B.1.177.75 | 0.993757 |
M | 93 | L93L | ctC | ctG | 862 | 862 | B.1.177.18 | 1 |
M | 93 | L93L | ctC | ctG | 835 | 835 | B.1.177.62 | 0.995232 |
M | 93 | L93L | ctC | ctG | 41 | 824 | B.1.617.2 | 0.000154 |
M | 93 | L93L | ctC | ctG | 805 | 805 | B.1.177.5 | 1 |
M | 93 | L93L | ctC | ctG | 772 | 772 | B.1.177.24 | 1 |
M | 93 | L93L | ctC | ctG | 750 | 750 | B.1.177.58 | 0.998668 |
M | 93 | L93L | ctC | ctG | 750 | 750 | B.1.177.9 | 0.998668 |
M | 93 | L93L | ctC | ctG | 739 | 739 | W.4 | 0.998649 |
M | 93 | L93L | ctC | ctG | 736 | 738 | B.1.177.32 | 0.993252 |
M | 93 | L93L | ctC | ctG | 699 | 699 | B.1.177.19 | 1 |
M | 93 | L93L | ctC | ctG | 674 | 674 | B.1.177.69 | 1 |
M | 93 | L93L | ctC | ctG | 674 | 674 | B.1.177.83 | 0.998519 |
M | 93 | L93L | ctC | ctG | 659 | 659 | B.1.177.20 | 1 |
M | 93 | L93L | ctC | ctG | 653 | 653 | B.1.177.43 | 0.964549 |
M | 93 | L93L | ctC | ctG | 607 | 607 | B.1.177.33 | 0.998355 |
M | 93 | L93L | ctC | ctG | 5 | 590 | AY.44 | 0.00003 |
M | 93 | L93L | ctC | ctG | 588 | 588 | B.1.177.11 | 0.998302 |
M | 93 | L93L | ctC | ctG | 567 | 567 | B.1.177.52 | 0.996485 |
M | 93 | L93L | ctC | ctG | 523 | 523 | B.1.177.80 | 1 |
M | 93 | L93L | ctC | ctG | 64 | 484 | AY.103 | 0.000397 |
M | 93 | L93L | ctC | ctG | 2 | 454 | AY.43 | 0.000009 |
M | 93 | L93L | ctC | ctG | 381 | 429 | B.1.177.55 | 0.888112 |
M | 93 | L93L | ctC | ctG | 427 | 427 | B.1.177.79 | 1 |
M | 93 | L93L | ctC | ctG | 416 | 416 | B.1.177.53 | 0.995215 |
M | 93 | L93L | ctC | ctG | 400 | 400 | B.1.177.41 | 1 |
M | 93 | L93L | ctC | ctG | 399 | 399 | B.1.177.76 | 0.995012 |
M | 93 | L93L | ctC | ctG | 398 | 398 | B.1.177.30 | 1 |
M | 93 | L93L | ctC | ctG | 162 | 395 | B.1.1 | 0.002939 |
M | 93 | L93L | ctC | ctG | 23 | 378 | B.1.2 | 0.000203 |
M | 93 | L93L | ctC | ctG | 370 | 370 | B.1.177.63 | 1 |
M | 93 | L93L | ctC | ctG | 320 | 320 | B.1.177.48 | 1 |
M | 93 | L93L | ctC | ctG | 313 | 314 | Z.1 | 0.904624 |
M | 93 | L93L | ctC | ctG | 297 | 300 | B.1.177.23 | 0.961165 |
M | 93 | L93L | ctC | ctG | 295 | 295 | B.1.177.72 | 1 |
M | 93 | L93L | ctC | ctG | 2 | 295 | P.1 | 0.000032 |
M | 93 | L93L | ctC | ctG | 259 | 259 | U.3 | 1 |
M | 93 | L93L | ctC | ctG | 1 | 232 | B.1.351 | 0.00003 |
M | 93 | L93L | ctC | ctG | 198 | 220 | B.1.177.2 | 0.9 |
M | 93 | L93L | ctC | ctG | 218 | 218 | B.1.177.51 | 0.995434 |
M | 93 | L93L | ctC | ctG | 212 | 212 | B.1.177.50 | 0.995305 |
M | 93 | L93L | ctC | ctG | 207 | 207 | W.2 | 1 |
M | 93 | L93L | ctC | ctG | 194 | 194 | B.1.177.40 | 1 |
M | 93 | L93L | ctC | ctG | 190 | 190 | W.3 | 1 |
M | 93 | L93L | ctC | ctG | 184 | 184 | B.1.177.85 | 1 |
M | 93 | L93L | ctC | ctG | 63 | 177 | B.1.221 | 0.004475 |
M | 93 | L93L | ctC | ctG | 167 | 167 | B.1.177.70 | 0.988166 |
M | 93 | L93L | ctC | ctG | 164 | 164 | B.1.177.14 | 1 |
M | 93 | L93L | ctC | ctG | 80 | 159 | B.1.160 | 0.002495 |
M | 93 | L93L | ctC | ctG | 150 | 150 | B.1.177.84 | 1 |
M | 93 | L93L | ctC | ctG | 143 | 143 | B.1.177.26 | 1 |
M | 93 | L93L | ctC | ctG | 104 | 139 | B.1.258 | 0.006921 |
M | 93 | L93L | ctC | ctG | 138 | 138 | AA.1 | 1 |
M | 93 | L93L | ctC | ctG | 135 | 135 | B.1.177.28 | 1 |
M | 93 | L93L | ctC | ctG | 131 | 131 | B.1.177.3 | 1 |
M | 93 | L93L | ctC | ctG | 131 | 131 | B.1.177.67 | 1 |
M | 93 | L93L | ctC | ctG | 130 | 130 | AA.2 | 1 |
M | 93 | L93L | ctC | ctG | 115 | 115 | W.1 | 1 |
M | 93 | L93L | ctC | ctG | 114 | 114 | B.1.160.30 | 0.339286 |
M | 93 | L93L | ctC | ctG | 1 | 112 | B.1.1.317 | 0.000412 |
M | 93 | L93L | ctC | ctG | 112 | 112 | U.2 | 0.982456 |
M | 93 | L93L | ctC | ctG | 110 | 110 | AA.4 | 1 |
M | 93 | L93L | ctC | ctG | 109 | 109 | AA.7 | 1 |
M | 93 | L93L | ctC | ctG | 92 | 107 | AY.120 | 0.00342 |
M | 93 | L93L | ctC | ctG | 7 | 107 | B.1.240 | 0.001509 |
M | 93 | L93L | ctC | ctG | 12 | 106 | AY.23 | 0.000837 |
M | 93 | L93L | ctC | ctG | 106 | 106 | B.1.177.27 | 1 |
M | 93 | L93L | ctC | ctG | 103 | 103 | B.1.177.78 | 1 |
M | 93 | L93L | ctC | ctG | 99 | 99 | B.1.177.71 | 1 |
M | 93 | L93L | ctC | ctG | 96 | 96 | B.1.177.38 | 1 |
M | 93 | L93L | ctC | ctG | 1 | 86 | B.1.243 | 0.00007 |
M | 93 | L93L | ctC | ctG | 81 | 81 | B.1.177.88 | 1 |
M | 93 | L93L | ctC | ctG | 79 | 79 | B.1.177.31 | 0.908046 |
M | 93 | L93L | ctC | ctG | 78 | 78 | U.1 | 1 |
M | 93 | L93L | ctC | ctG | 78 | 78 | Y.1 | 1 |
M | 93 | L93L | ctC | ctG | 77 | 77 | B.1.177.47 | 1 |
M | 93 | L93L | ctC | ctG | 67 | 67 | B.1.177.25 | 1 |
M | 93 | L93L | ctC | ctG | 66 | 66 | B.1.177.68 | 1 |
M | 93 | L93L | ctC | ctG | 66 | 66 | B.1.177.74 | 1 |
M | 93 | L93L | ctC | ctG | 65 | 65 | B.1.177.39 | 1 |
M | 93 | L93L | ctC | ctG | 2 | 65 | B.1.596 | 0.000174 |
M | 93 | L93L | ctC | ctG | 62 | 62 | AA.5 | 1 |
M | 93 | L93L | ctC | ctG | 62 | 62 | AA.6 | 1 |
M | 93 | L93L | ctC | ctG | 62 | 62 | B.1.177.36 | 1 |
M | 93 | L93L | ctC | ctG | 62 | 62 | B.1.177.59 | 1 |
M | 93 | L93L | ctC | ctG | 25 | 54 | B.1.36 | 0.003648 |
M | 93 | L93L | ctC | ctG | 1 | 51 | B.1.126 | 0.001276 |
M | 93 | L93L | ctC | ctG | 1 | 47 | AY.4.2 | 0.000022 |
M | 93 | L93L | ctC | ctG | 45 | 45 | AA.8 | 1 |
M | 93 | L93L | ctC | ctG | 44 | 44 | V.1 | 1 |
M | 93 | L93L | ctC | ctG | 41 | 41 | B.1.177.89 | 1 |
M | 93 | L93L | ctC | ctG | 37 | 37 | AA.3 | 1 |
M | 93 | L93L | ctC | ctG | 37 | 37 | B.1.177.37 | 1 |
M | 93 | L93L | ctC | ctG | 31 | 31 | V.2 | 1 |
M | 93 | L93L | ctC | ctG | 30 | 30 | B.1.160.20 | 0.267857 |
M | 93 | L93L | ctC | ctG | 27 | 27 | B.1.177.49 | 1 |
M | 93 | L93L | ctC | ctG | 1 | 26 | AY.13 | 0.000161 |
M | 93 | L93L | ctC | ctG | 1 | 26 | B.1.1.385 | 0.004464 |
M | 93 | L93L | ctC | ctG | 24 | 24 | B.1.177.66 | 1 |
M | 93 | L93L | ctC | ctG | 1 | 24 | Q.3 | 0.000145 |
M | 93 | L93L | ctC | ctG | 23 | 23 | B.1.177.61 | 1 |
M | 93 | L93L | ctC | ctG | 4 | 22 | B.1.160.16 | 0.003717 |
M | 93 | L93L | ctC | ctG | 16 | 18 | B.1.1.39 | 0.008155 |
M | 93 | L93L | ctC | ctG | 1 | 17 | Q.1 | 0.000126 |
M | 93 | L93L | ctC | ctG | 10 | 16 | B | 0.001278 |
M | 93 | L93L | ctC | ctG | 5 | 16 | B.1.1.37 | 0.000964 |
M | 93 | L93L | ctC | ctG | 14 | 14 | B.1.177.29 | 0.933333 |
M | 93 | L93L | ctC | ctG | 13 | 13 | B.1.177.34 | 0.684211 |
M | 93 | L93L | ctC | ctG | 1 | 12 | AY.46 | 0.000104 |
M | 93 | L93L | ctC | ctG | 1 | 12 | AY.9 | 0.000068 |
M | 93 | L93L | ctC | ctG | 12 | 12 | B.1.160.28 | 0.035088 |
M | 93 | L93L | ctC | ctG | 11 | 11 | B.1.177.64 | 1 |
M | 93 | L93L | ctC | ctG | 2 | 11 | P.2 | 0.000373 |
M | 93 | L93L | ctC | ctG | 7 | 9 | B.1.1.70 | 0.002387 |
M | 93 | L93L | ctC | ctG | 4 | 9 | B.1.509 | 0.003463 |
M | 93 | L93L | ctC | ctG | 1 | 9 | B.1.575 | 0.000303 |
M | 93 | L93L | ctC | ctG | 1 | 9 | B.1.595 | 0.000261 |
M | 93 | L93L | ctC | ctG | 1 | 8 | A.2.5 | 0.000499 |
M | 93 | L93L | ctC | ctG | 8 | 8 | B.1.160.32 | 0.034335 |
M | 93 | L93L | ctC | ctG | 5 | 8 | B.1.258.11 | 0.001982 |
M | 93 | L93L | ctC | ctG | 2 | 8 | B.1.258.17 | 0.000208 |
M | 93 | L93L | ctC | ctG | 1 | 8 | B.1.609 | 0.000479 |
M | 93 | L93L | ctC | ctG | 1 | 7 | 0.055556 | |
M | 93 | L93L | ctC | ctG | 5 | 7 | B.1.36.39 | 0.011086 |
M | 93 | L93L | ctC | ctG | 1 | 6 | AD.2 | 0.000219 |
M | 93 | L93L | ctC | ctG | 5 | 6 | B.1.416.1 | 0.007812 |
M | 93 | L93L | ctC | ctG | 1 | 5 | B.1.1.1 | 0.000327 |
M | 93 | L93L | ctC | ctG | 4 | 5 | B.1.1.170 | 0.004988 |
M | 93 | L93L | ctC | ctG | 1 | 5 | B.1.617.1 | 0.000129 |
M | 93 | L93L | ctC | ctG | 1 | 4 | B.1.1.372 | 0.000689 |
M | 93 | L93L | ctC | ctG | 4 | 4 | B.1.473 | 0.076923 |
M | 93 | L93L | ctC | ctG | 2 | 4 | P.1.12 | 0.000968 |
M | 93 | L93L | ctC | ctG | 2 | 3 | A | 0.000774 |
M | 93 | L93L | ctC | ctG | 3 | 3 | AP.1 | 0.004505 |
M | 93 | L93L | ctC | ctG | 1 | 3 | B.1.1.25 | 0.000569 |
M | 93 | L93L | ctC | ctG | 3 | 3 | B.1.1.311 | 0.001074 |
M | 93 | L93L | ctC | ctG | 3 | 3 | B.1.1.315 | 0.025424 |
M | 93 | L93L | ctC | ctG | 2 | 3 | B.1.1.521 | 0.010695 |
M | 93 | L93L | ctC | ctG | 3 | 3 | B.1.160.14 | 0.006356 |
M | 93 | L93L | ctC | ctG | 2 | 3 | B.1.36.17 | 0.000988 |
M | 93 | L93L | ctC | ctG | 3 | 3 | B.1.375 | 0.002459 |
M | 93 | L93L | ctC | ctG | 1 | 2 | A.21 | 0.00277 |
M | 93 | L93L | ctC | ctG | 1 | 2 | B.1.1.189 | 0.001513 |
M | 93 | L93L | ctC | ctG | 2 | 2 | B.1.160.10 | 0.016129 |
M | 93 | L93L | ctC | ctG | 2 | 2 | B.1.236 | 0.004107 |
M | 93 | L93L | ctC | ctG | 1 | 2 | B.1.540 | 0.009709 |
M | 93 | L93L | ctC | ctG | 2 | 2 | C.30 | 0.003454 |
M | 93 | L93L | ctC | ctG | 1 | 1 | AF.1 | 0.037037 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.1.409 | 0.002833 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.1.47 | 0.005348 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.160.12 | 0.00641 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.281 | 0.021739 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.326 | 0.007576 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.36.35 | 0.002604 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.36.9 | 0.003215 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.367 | 0.000792 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.379 | 0.017241 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.389 | 0.001002 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.391 | 0.001127 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.576 | 0.000907 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.581 | 0.009434 |
M | 93 | L93L | ctC | ctG | 1 | 1 | B.1.599 | 0.00365 |
M | 93 | L93L | ctC | ctG | 1 | 1 | K.1 | 0.02381 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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