CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
M | 29 | L29F | nonsyn | Ctt | Ttt | 5596 | 5596 | 1 | 26607-26609 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
M | 29 | L29F | Ctt | Ttt | 5596 | 5596 | All | 0.00107 |
M | 29 | L29F | Ctt | Ttt | 1648 | 1648 | AY.1 | 0.652157 |
M | 29 | L29F | Ctt | Ttt | 655 | 655 | B.1.1.7 | 0.000586 |
M | 29 | L29F | Ctt | Ttt | 382 | 382 | AY.93 | 0.104315 |
M | 29 | L29F | Ctt | Ttt | 310 | 310 | AY.103 | 0.001925 |
M | 29 | L29F | Ctt | Ttt | 275 | 275 | AY.4 | 0.000428 |
M | 29 | L29F | Ctt | Ttt | 264 | 264 | B.1.617.2 | 0.000994 |
M | 29 | L29F | Ctt | Ttt | 153 | 153 | C.1.2 | 0.651064 |
M | 29 | L29F | Ctt | Ttt | 128 | 128 | B.1.632 | 0.85906 |
M | 29 | L29F | Ctt | Ttt | 106 | 106 | AY.120 | 0.003941 |
M | 29 | L29F | Ctt | Ttt | 100 | 100 | B.1.2 | 0.000881 |
M | 29 | L29F | Ctt | Ttt | 72 | 72 | AY.69 | 0.01344 |
M | 29 | L29F | Ctt | Ttt | 68 | 68 | AY.44 | 0.000414 |
M | 29 | L29F | Ctt | Ttt | 66 | 66 | AY.43 | 0.000292 |
M | 29 | L29F | Ctt | Ttt | 61 | 61 | AY.25 | 0.000367 |
M | 29 | L29F | Ctt | Ttt | 53 | 53 | P.1.14 | 0.002533 |
M | 29 | L29F | Ctt | Ttt | 52 | 52 | AY.33 | 0.003472 |
M | 29 | L29F | Ctt | Ttt | 52 | 52 | P.1 | 0.000819 |
M | 29 | L29F | Ctt | Ttt | 42 | 42 | B.1.1 | 0.000762 |
M | 29 | L29F | Ctt | Ttt | 41 | 41 | AY.3 | 0.000408 |
M | 29 | L29F | Ctt | Ttt | 41 | 41 | B.1.1.63 | 0.015818 |
M | 29 | L29F | Ctt | Ttt | 38 | 38 | AY.39 | 0.000939 |
M | 29 | L29F | Ctt | Ttt | 37 | 37 | B.1 | 0.000339 |
M | 29 | L29F | Ctt | Ttt | 36 | 36 | AY.117 | 0.003043 |
M | 29 | L29F | Ctt | Ttt | 35 | 35 | AY.48 | 0.016279 |
M | 29 | L29F | Ctt | Ttt | 26 | 26 | AY.9.2 | 0.000955 |
M | 29 | L29F | Ctt | Ttt | 25 | 25 | AY.20 | 0.000972 |
M | 29 | L29F | Ctt | Ttt | 24 | 24 | AY.29 | 0.000379 |
M | 29 | L29F | Ctt | Ttt | 23 | 23 | B.1.351 | 0.000684 |
M | 29 | L29F | Ctt | Ttt | 22 | 22 | AY.110 | 0.002479 |
M | 29 | L29F | Ctt | Ttt | 22 | 22 | B.1.214.2 | 0.013189 |
M | 29 | L29F | Ctt | Ttt | 22 | 22 | C.36.3.1 | 0.059783 |
M | 29 | L29F | Ctt | Ttt | 21 | 21 | AY.47 | 0.000653 |
M | 29 | L29F | Ctt | Ttt | 21 | 21 | AY.5 | 0.000434 |
M | 29 | L29F | Ctt | Ttt | 19 | 19 | AY.14 | 0.001672 |
M | 29 | L29F | Ctt | Ttt | 17 | 17 | B.1.160 | 0.00053 |
M | 29 | L29F | Ctt | Ttt | 16 | 16 | AY.102 | 0.000424 |
M | 29 | L29F | Ctt | Ttt | 16 | 16 | AY.54 | 0.001526 |
M | 29 | L29F | Ctt | Ttt | 16 | 16 | B.1.1.429 | 0.073733 |
M | 29 | L29F | Ctt | Ttt | 16 | 16 | B.1.243 | 0.001113 |
M | 29 | L29F | Ctt | Ttt | 16 | 16 | B.6.2 | 1 |
M | 29 | L29F | Ctt | Ttt | 16 | 16 | Q.2 | 0.009816 |
M | 29 | L29F | Ctt | Ttt | 15 | 15 | B.1.177 | 0.000198 |
M | 29 | L29F | Ctt | Ttt | 15 | 15 | B.1.36 | 0.002189 |
M | 29 | L29F | Ctt | Ttt | 14 | 14 | AY.39.2 | 0.021572 |
M | 29 | L29F | Ctt | Ttt | 14 | 14 | B.1.1.291 | 0.010393 |
M | 29 | L29F | Ctt | Ttt | 13 | 13 | AY.42 | 0.000523 |
M | 29 | L29F | Ctt | Ttt | 11 | 11 | A | 0.004257 |
M | 29 | L29F | Ctt | Ttt | 11 | 11 | AY.118 | 0.000689 |
M | 29 | L29F | Ctt | Ttt | 11 | 11 | AY.46 | 0.001145 |
M | 29 | L29F | Ctt | Ttt | 11 | 11 | B.1.1.304 | 0.030899 |
M | 29 | L29F | Ctt | Ttt | 10 | 10 | AY.107 | 0.00466 |
M | 29 | L29F | Ctt | Ttt | 10 | 10 | AY.75 | 0.00056 |
M | 29 | L29F | Ctt | Ttt | 10 | 10 | B.1.1.50 | 0.006789 |
M | 29 | L29F | Ctt | Ttt | 10 | 10 | B.1.160.32 | 0.042918 |
M | 29 | L29F | Ctt | Ttt | 9 | 9 | AY.4.2 | 0.000195 |
M | 29 | L29F | Ctt | Ttt | 9 | 9 | AY.45 | 0.001095 |
M | 29 | L29F | Ctt | Ttt | 9 | 9 | AY.9.1 | 0.000754 |
M | 29 | L29F | Ctt | Ttt | 9 | 9 | B.1.540 | 0.087379 |
M | 29 | L29F | Ctt | Ttt | 8 | 8 | AY.121 | 0.001083 |
M | 29 | L29F | Ctt | Ttt | 8 | 8 | B.1.1.207 | 0.009456 |
M | 29 | L29F | Ctt | Ttt | 8 | 8 | B.1.1.306 | 0.003507 |
M | 29 | L29F | Ctt | Ttt | 8 | 8 | B.1.1.519 | 0.000318 |
M | 29 | L29F | Ctt | Ttt | 8 | 8 | P.2 | 0.001493 |
M | 29 | L29F | Ctt | Ttt | 7 | 7 | AY.100 | 0.000322 |
M | 29 | L29F | Ctt | Ttt | 7 | 7 | AY.74 | 0.00081 |
M | 29 | L29F | Ctt | Ttt | 6 | 6 | AY.119 | 0.000212 |
M | 29 | L29F | Ctt | Ttt | 6 | 6 | AY.64 | 0.003571 |
M | 29 | L29F | Ctt | Ttt | 6 | 6 | AY.7.1 | 0.000676 |
M | 29 | L29F | Ctt | Ttt | 6 | 6 | B.1.1.214 | 0.000333 |
M | 29 | L29F | Ctt | Ttt | 6 | 6 | B.1.221 | 0.000426 |
M | 29 | L29F | Ctt | Ttt | 6 | 6 | B.1.429 | 0.000141 |
M | 29 | L29F | Ctt | Ttt | 6 | 6 | B.1.526 | 0.000141 |
M | 29 | L29F | Ctt | Ttt | 5 | 5 | AY.26 | 0.000142 |
M | 29 | L29F | Ctt | Ttt | 5 | 5 | B.1.1.416 | 0.004525 |
M | 29 | L29F | Ctt | Ttt | 5 | 5 | B.1.36.8 | 0.005 |
M | 29 | L29F | Ctt | Ttt | 5 | 5 | B.1.427 | 0.000252 |
M | 29 | L29F | Ctt | Ttt | 5 | 5 | C.37 | 0.00058 |
M | 29 | L29F | Ctt | Ttt | 5 | 5 | P.1.15 | 0.001162 |
M | 29 | L29F | Ctt | Ttt | 5 | 5 | Q.8 | 0.000825 |
M | 29 | L29F | Ctt | Ttt | 4 | 4 | AY.106 | 0.00134 |
M | 29 | L29F | Ctt | Ttt | 4 | 4 | AY.23 | 0.000279 |
M | 29 | L29F | Ctt | Ttt | 4 | 4 | AY.35 | 0.000932 |
M | 29 | L29F | Ctt | Ttt | 4 | 4 | AY.4.5 | 0.00043 |
M | 29 | L29F | Ctt | Ttt | 4 | 4 | AY.6 | 0.000165 |
M | 29 | L29F | Ctt | Ttt | 4 | 4 | AY.62 | 0.001743 |
M | 29 | L29F | Ctt | Ttt | 4 | 4 | B.1.234 | 0.000528 |
M | 29 | L29F | Ctt | Ttt | 4 | 4 | B.1.258 | 0.000266 |
M | 29 | L29F | Ctt | Ttt | 4 | 4 | B.1.398 | 0.011905 |
M | 29 | L29F | Ctt | Ttt | 4 | 4 | B.1.525 | 0.000453 |
M | 29 | L29F | Ctt | Ttt | 4 | 4 | P.1.7 | 0.001277 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | AY.10 | 0.00159 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | AY.105 | 0.001929 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | AY.116.1 | 0.000934 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | AY.120.1 | 0.000963 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | AY.13 | 0.000483 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | AY.16 | 0.001139 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | AY.46.4 | 0.000494 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | AY.98 | 0.000237 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | B.1.1.219 | 0.015 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | B.1.1.294 | 0.003797 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | B.1.1.37 | 0.000579 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | B.1.595 | 0.000783 |
M | 29 | L29F | Ctt | Ttt | 3 | 3 | L.3 | 0.010638 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | A.2 | 0.001324 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | A.2.5 | 0.000998 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | AY.104 | 0.003968 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | AY.19 | 0.002281 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | AY.39.1 | 0.000079 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | AY.46.6 | 0.000144 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | AY.84 | 0.000875 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | AY.9 | 0.000135 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | AY.95 | 0.001522 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | AY.98.1 | 0.000097 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B | 0.000256 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.1.28 | 0.000622 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.1.317 | 0.000823 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.1.412 | 0.015267 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.1.434 | 0.000697 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.177.5 | 0.002484 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.177.73 | 0.001133 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.237 | 0.00995 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.258.17 | 0.000208 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.36.29 | 0.001035 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.36.9 | 0.006431 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.361 | 0.002577 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.617.1 | 0.000258 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.623 | 0.001073 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.1.637 | 0.000146 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | B.40 | 0.000729 |
M | 29 | L29F | Ctt | Ttt | 2 | 2 | D.2 | 0.00015 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | A.29 | 0.005319 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AD.2 | 0.000219 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AE.1 | 0.011364 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AT.1 | 0.005128 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.108 | 0.001103 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.111 | 0.000183 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.113 | 0.000142 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.114 | 0.000231 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.116 | 0.000287 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.12 | 0.000316 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.120.2 | 0.001285 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.16.1 | 0.00047 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.21 | 0.001898 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.22 | 0.002092 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.24 | 0.000431 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.3.1 | 0.000085 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.34 | 0.000097 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.36 | 0.000148 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.4.2.1 | 0.000149 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.40 | 0.000964 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.46.5 | 0.000198 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.5.3 | 0.000337 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.5.4 | 0.000277 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.50 | 0.000799 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.53 | 0.000288 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.56 | 0.001605 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.59 | 0.00053 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.67 | 0.000464 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.68 | 0.000274 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.7 | 0.000196 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.70 | 0.000209 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.71 | 0.000475 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.73 | 0.000665 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.75.1 | 0.00018 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.76 | 0.004831 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.78 | 0.001541 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.79 | 0.001211 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.82 | 0.001357 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.83 | 0.001724 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.85 | 0.000427 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.86 | 0.00083 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.87 | 0.000833 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.91 | 0.00073 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.92 | 0.000287 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | AY.99.2 | 0.000092 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.1.117 | 0.009709 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.1.138 | 0.006061 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.1.222 | 0.000204 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.1.243 | 0.004082 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.1.284 | 0.000107 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.1.311 | 0.000358 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.1.348 | 0.000796 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.110.3 | 0.000718 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.157 | 0.002985 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.160.17 | 0.001701 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.177.57 | 0.000281 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.177.7 | 0.000165 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.177.85 | 0.005435 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.214 | 0.003663 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.236 | 0.002053 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.241 | 0.000812 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.258.14 | 0.00098 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.311 | 0.000275 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.336 | 0.002439 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.351.5 | 0.0006 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.36.17 | 0.000494 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.36.24 | 0.006173 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.36.39 | 0.002217 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.403 | 0.003268 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.467 | 0.04 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.470 | 0.001404 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.541 | 0.004425 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.564 | 0.000426 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.570 | 0.002941 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.575 | 0.000303 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.576 | 0.000907 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.596 | 0.000087 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.621 | 0.000089 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.1.628 | 0.000352 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | B.12 | 0.00641 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | C.14 | 0.004329 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | P.1.12 | 0.000484 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | Q.4 | 0.000455 |
M | 29 | L29F | Ctt | Ttt | 1 | 1 | R.1 | 0.00009 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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