CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
M | 135 | E135E | syn | gaA | gaG | 7843 | 7843 | 1 | 26925-26927 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
M | 135 | E135E | gaA | gaG | 7843 | 7843 | All | 0.0015 |
M | 135 | E135E | gaA | gaG | 1962 | 1962 | B.1.1.7 | 0.001756 |
M | 135 | E135E | gaA | gaG | 881 | 881 | AY.26 | 0.024941 |
M | 135 | E135E | gaA | gaG | 871 | 871 | AY.4 | 0.001356 |
M | 135 | E135E | gaA | gaG | 833 | 833 | B.1.1.207 | 0.984634 |
M | 135 | E135E | gaA | gaG | 818 | 818 | B.1.1 | 0.014839 |
M | 135 | E135E | gaA | gaG | 280 | 280 | L.3 | 0.992908 |
M | 135 | E135E | gaA | gaG | 216 | 216 | B.1.617.2 | 0.000813 |
M | 135 | E135E | gaA | gaG | 189 | 189 | AY.3 | 0.00188 |
M | 135 | E135E | gaA | gaG | 158 | 158 | B.1 | 0.001447 |
M | 135 | E135E | gaA | gaG | 141 | 141 | AY.43 | 0.000625 |
M | 135 | E135E | gaA | gaG | 131 | 131 | B.1.160 | 0.004086 |
M | 135 | E135E | gaA | gaG | 86 | 86 | AY.44 | 0.000523 |
M | 135 | E135E | gaA | gaG | 69 | 69 | AY.103 | 0.000428 |
M | 135 | E135E | gaA | gaG | 67 | 67 | P.1 | 0.001056 |
M | 135 | E135E | gaA | gaG | 49 | 49 | B.1.2 | 0.000431 |
M | 135 | E135E | gaA | gaG | 48 | 48 | AY.25 | 0.000289 |
M | 135 | E135E | gaA | gaG | 47 | 47 | AY.42 | 0.001891 |
M | 135 | E135E | gaA | gaG | 45 | 45 | B.1.351 | 0.001338 |
M | 135 | E135E | gaA | gaG | 42 | 42 | AY.69 | 0.00784 |
M | 135 | E135E | gaA | gaG | 40 | 40 | AY.102 | 0.001061 |
M | 135 | E135E | gaA | gaG | 39 | 39 | B.1.637 | 0.00285 |
M | 135 | E135E | gaA | gaG | 38 | 38 | AY.5 | 0.000785 |
M | 135 | E135E | gaA | gaG | 23 | 23 | AY.39 | 0.000568 |
M | 135 | E135E | gaA | gaG | 23 | 23 | AY.94 | 0.010181 |
M | 135 | E135E | gaA | gaG | 21 | 21 | B.1.1.419 | 0.155556 |
M | 135 | E135E | gaA | gaG | 18 | 18 | AY.16 | 0.006834 |
M | 135 | E135E | gaA | gaG | 18 | 18 | AY.20 | 0.0007 |
M | 135 | E135E | gaA | gaG | 18 | 18 | AY.6 | 0.00074 |
M | 135 | E135E | gaA | gaG | 18 | 18 | B.1.1.519 | 0.000715 |
M | 135 | E135E | gaA | gaG | 18 | 18 | C.36.3 | 0.01021 |
M | 135 | E135E | gaA | gaG | 17 | 17 | AY.57 | 0.011155 |
M | 135 | E135E | gaA | gaG | 16 | 16 | P.2 | 0.002986 |
M | 135 | E135E | gaA | gaG | 14 | 14 | AY.29 | 0.000221 |
M | 135 | E135E | gaA | gaG | 14 | 14 | AY.4.2 | 0.000304 |
M | 135 | E135E | gaA | gaG | 14 | 14 | B.1.1.189 | 0.02118 |
M | 135 | E135E | gaA | gaG | 13 | 13 | AY.120 | 0.000483 |
M | 135 | E135E | gaA | gaG | 13 | 13 | B.1.526 | 0.000306 |
M | 135 | E135E | gaA | gaG | 11 | 11 | AY.33 | 0.000735 |
M | 135 | E135E | gaA | gaG | 11 | 11 | AY.9.1 | 0.000921 |
M | 135 | E135E | gaA | gaG | 11 | 11 | B.1.177 | 0.000145 |
M | 135 | E135E | gaA | gaG | 11 | 11 | C.4 | 0.11 |
M | 135 | E135E | gaA | gaG | 10 | 10 | AY.118 | 0.000626 |
M | 135 | E135E | gaA | gaG | 10 | 10 | B.1.427 | 0.000505 |
M | 135 | E135E | gaA | gaG | 10 | 10 | B.1.453 | 0.032362 |
M | 135 | E135E | gaA | gaG | 10 | 10 | B.1.631 | 0.03367 |
M | 135 | E135E | gaA | gaG | 10 | 10 | R.1 | 0.0009 |
M | 135 | E135E | gaA | gaG | 9 | 9 | AY.121 | 0.001218 |
M | 135 | E135E | gaA | gaG | 9 | 9 | AY.27 | 0.000582 |
M | 135 | E135E | gaA | gaG | 9 | 9 | AY.61 | 0.000943 |
M | 135 | E135E | gaA | gaG | 9 | 9 | B.1.621 | 0.000797 |
M | 135 | E135E | gaA | gaG | 8 | 8 | AY.100 | 0.000368 |
M | 135 | E135E | gaA | gaG | 8 | 8 | AY.111 | 0.001465 |
M | 135 | E135E | gaA | gaG | 8 | 8 | AY.113 | 0.001139 |
M | 135 | E135E | gaA | gaG | 8 | 8 | AY.119 | 0.000282 |
M | 135 | E135E | gaA | gaG | 8 | 8 | B.1.1.270 | 0.082474 |
M | 135 | E135E | gaA | gaG | 8 | 8 | P.1.16 | 0.002993 |
M | 135 | E135E | gaA | gaG | 7 | 7 | AY.23 | 0.000488 |
M | 135 | E135E | gaA | gaG | 7 | 7 | AY.47 | 0.000218 |
M | 135 | E135E | gaA | gaG | 7 | 7 | AY.54 | 0.000667 |
M | 135 | E135E | gaA | gaG | 7 | 7 | AY.98 | 0.000553 |
M | 135 | E135E | gaA | gaG | 7 | 7 | B.1.234 | 0.000924 |
M | 135 | E135E | gaA | gaG | 7 | 7 | B.1.409 | 0.005469 |
M | 135 | E135E | gaA | gaG | 6 | 6 | AY.117 | 0.000507 |
M | 135 | E135E | gaA | gaG | 6 | 6 | AY.14 | 0.000528 |
M | 135 | E135E | gaA | gaG | 6 | 6 | AY.59 | 0.003178 |
M | 135 | E135E | gaA | gaG | 6 | 6 | B.1.177.81 | 0.001136 |
M | 135 | E135E | gaA | gaG | 6 | 6 | B.1.243 | 0.000418 |
M | 135 | E135E | gaA | gaG | 6 | 6 | P.1.14 | 0.000287 |
M | 135 | E135E | gaA | gaG | 6 | 6 | Q.1 | 0.000758 |
M | 135 | E135E | gaA | gaG | 5 | 5 | AY.46.2 | 0.003177 |
M | 135 | E135E | gaA | gaG | 5 | 5 | B.1.221 | 0.000355 |
M | 135 | E135E | gaA | gaG | 5 | 5 | B.1.567 | 0.016667 |
M | 135 | E135E | gaA | gaG | 5 | 5 | D.2 | 0.000375 |
M | 135 | E135E | gaA | gaG | 4 | 4 | AY.4.2.1 | 0.000596 |
M | 135 | E135E | gaA | gaG | 4 | 4 | AY.46 | 0.000416 |
M | 135 | E135E | gaA | gaG | 4 | 4 | AY.75.1 | 0.000721 |
M | 135 | E135E | gaA | gaG | 4 | 4 | AY.9 | 0.00027 |
M | 135 | E135E | gaA | gaG | 4 | 4 | AY.98.1 | 0.000194 |
M | 135 | E135E | gaA | gaG | 4 | 4 | B | 0.000511 |
M | 135 | E135E | gaA | gaG | 4 | 4 | B.1.189 | 0.017167 |
M | 135 | E135E | gaA | gaG | 4 | 4 | B.1.258.17 | 0.000416 |
M | 135 | E135E | gaA | gaG | 4 | 4 | B.1.258.24 | 0.043011 |
M | 135 | E135E | gaA | gaG | 4 | 4 | B.1.36.1 | 0.004561 |
M | 135 | E135E | gaA | gaG | 4 | 4 | B.1.429 | 0.000094 |
M | 135 | E135E | gaA | gaG | 4 | 4 | B.1.525 | 0.000453 |
M | 135 | E135E | gaA | gaG | 4 | 4 | B.1.595 | 0.001044 |
M | 135 | E135E | gaA | gaG | 4 | 4 | B.1.596 | 0.000349 |
M | 135 | E135E | gaA | gaG | 4 | 4 | B.1.617.3 | 0.01194 |
M | 135 | E135E | gaA | gaG | 4 | 4 | Q.8 | 0.00066 |
M | 135 | E135E | gaA | gaG | 3 | 3 | AD.2 | 0.000657 |
M | 135 | E135E | gaA | gaG | 3 | 3 | AY.30 | 0.001187 |
M | 135 | E135E | gaA | gaG | 3 | 3 | AY.71 | 0.001425 |
M | 135 | E135E | gaA | gaG | 3 | 3 | AY.99.2 | 0.000276 |
M | 135 | E135E | gaA | gaG | 3 | 3 | B.1.1.200 | 0.022388 |
M | 135 | E135E | gaA | gaG | 3 | 3 | B.1.1.306 | 0.001315 |
M | 135 | E135E | gaA | gaG | 3 | 3 | B.1.177.4 | 0.000633 |
M | 135 | E135E | gaA | gaG | 3 | 3 | B.1.177.82 | 0.001432 |
M | 135 | E135E | gaA | gaG | 3 | 3 | B.1.596.1 | 0.028037 |
M | 135 | E135E | gaA | gaG | 3 | 3 | C.1 | 0.007177 |
M | 135 | E135E | gaA | gaG | 3 | 3 | C.35 | 0.002322 |
M | 135 | E135E | gaA | gaG | 3 | 3 | C.37 | 0.000348 |
M | 135 | E135E | gaA | gaG | 3 | 3 | P.1.15 | 0.000697 |
M | 135 | E135E | gaA | gaG | 2 | 2 | A.5 | 0.003846 |
M | 135 | E135E | gaA | gaG | 2 | 2 | AY.16.1 | 0.00094 |
M | 135 | E135E | gaA | gaG | 2 | 2 | AY.35 | 0.000466 |
M | 135 | E135E | gaA | gaG | 2 | 2 | AY.39.1 | 0.000079 |
M | 135 | E135E | gaA | gaG | 2 | 2 | AY.45 | 0.000243 |
M | 135 | E135E | gaA | gaG | 2 | 2 | AY.46.4 | 0.000329 |
M | 135 | E135E | gaA | gaG | 2 | 2 | AY.7 | 0.000392 |
M | 135 | E135E | gaA | gaG | 2 | 2 | AY.75 | 0.000112 |
M | 135 | E135E | gaA | gaG | 2 | 2 | AY.8 | 0.001212 |
M | 135 | E135E | gaA | gaG | 2 | 2 | AY.84 | 0.000875 |
M | 135 | E135E | gaA | gaG | 2 | 2 | AY.91 | 0.001461 |
M | 135 | E135E | gaA | gaG | 2 | 2 | AY.95 | 0.001522 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.1.1 | 0.000653 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.1.176 | 0.000879 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.1.25 | 0.001137 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.1.28 | 0.000622 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.1.336 | 0.033333 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.1.348 | 0.001592 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.1.372 | 0.001377 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.1.409 | 0.005666 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.1.448 | 0.004065 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.1.464 | 0.002946 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.1.70 | 0.000682 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.210 | 0.004264 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.459 | 0.008163 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.466.2 | 0.000782 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.1.505 | 0.008772 |
M | 135 | E135E | gaA | gaG | 2 | 2 | B.46 | 0.041667 |
M | 135 | E135E | gaA | gaG | 1 | 1 | A | 0.000387 |
M | 135 | E135E | gaA | gaG | 1 | 1 | A.1 | 0.000282 |
M | 135 | E135E | gaA | gaG | 1 | 1 | A.3 | 0.002096 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AU.2 | 0.002421 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.101 | 0.00049 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.104 | 0.001984 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.105 | 0.000643 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.110 | 0.000113 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.114 | 0.000231 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.116 | 0.000287 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.12 | 0.000316 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.3.1 | 0.000085 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.34 | 0.000097 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.4.3 | 0.000842 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.4.5 | 0.000107 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.41 | 0.000294 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.46.6 | 0.000072 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.52 | 0.000814 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.53 | 0.000288 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.55 | 0.000917 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.64 | 0.000595 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.67 | 0.000464 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.7.1 | 0.000113 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.74 | 0.000116 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.9.2 | 0.000037 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.92 | 0.000287 |
M | 135 | E135E | gaA | gaG | 1 | 1 | AY.93 | 0.000273 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.222 | 0.000204 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.279 | 0.001121 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.284 | 0.000107 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.301 | 0.001179 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.304 | 0.002809 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.311 | 0.000358 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.317 | 0.000412 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.318 | 0.000302 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.322 | 0.008772 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.351 | 0.002793 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.37 | 0.000193 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.4 | 0.002976 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.402 | 0.011111 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.416 | 0.000905 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.486 | 0.001577 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.1.525 | 0.005464 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.103 | 0.019231 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.110.3 | 0.000718 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.127 | 0.002198 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.128 | 0.000635 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.177.18 | 0.00116 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.177.21 | 0.000076 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.177.31 | 0.011494 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.177.57 | 0.000281 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.177.60 | 0.000218 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.177.73 | 0.000566 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.206 | 0.000816 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.212 | 0.016667 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.214.1 | 0.02 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.215 | 0.009615 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.22.1 | 0.03125 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.265 | 0.001271 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.279 | 0.000514 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.291 | 0.019231 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.329 | 0.000608 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.36 | 0.000146 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.36.26 | 0.002857 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.36.29 | 0.000517 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.36.39 | 0.002217 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.36.7 | 0.004 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.375 | 0.00082 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.391 | 0.001127 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.404 | 0.001302 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.411 | 0.003704 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.422 | 0.000812 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.438.1 | 0.000107 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.468 | 0.005714 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.469 | 0.00361 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.480 | 0.002488 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.499 | 0.00105 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.501 | 0.007353 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.517 | 0.000427 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.565 | 0.00081 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.575 | 0.000303 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.600 | 0.005848 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.617.1 | 0.000129 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.628 | 0.000352 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.636 | 0.006711 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.1.9.4 | 0.006135 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.11 | 0.005128 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.31 | 0.003731 |
M | 135 | E135E | gaA | gaG | 1 | 1 | B.55 | 0.00295 |
M | 135 | E135E | gaA | gaG | 1 | 1 | P.1.17 | 0.000162 |
M | 135 | E135E | gaA | gaG | 1 | 1 | P.1.2 | 0.001156 |
M | 135 | E135E | gaA | gaG | 1 | 1 | P.1.7 | 0.000319 |
M | 135 | E135E | gaA | gaG | 1 | 1 | P.6 | 0.003145 |
M | 135 | E135E | gaA | gaG | 1 | 1 | Q.3 | 0.000145 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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