CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = E : CodonNum = 75 & Codon = gtT

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
E	75	V75V		syn	gtC	gtT	2054	1654	0.805258	26467-26469

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
E	75	V75V	gtC	gtT	1654	2054	All	0.000316
E	75	V75V	gtC	gtT	885	885	B.1.214.2	0.530576
E	75	V75V	gtC	gtT	169	175	B.1.1.7	0.000151
E	75	V75V	gtC	gtT	147	147	B.1.177.4	0.031026
E	75	V75V	gtC	gtT	42	71	AY.4	0.000065
E	75	V75V	gtC	gtT	27	63	B.1	0.000247
E	75	V75V	gtC	gtT	41	45	B.1.617.2	0.000154
E	75	V75V	gtC	gtT	38	38	B.1.1.198	0.0558
E	75	V75V	gtC	gtT	7	30	B.1.1	0.000127
E	75	V75V	gtC	gtT	8	21	B.1.258	0.000532
E	75	V75V	gtC	gtT	21	21	P.1	0.000331
E	75	V75V	gtC	gtT	17	18	B.1.2	0.00015
E	75	V75V	gtC	gtT	16	16	B.1.214.3	0.114286
E	75	V75V	gtC	gtT	12	15	AY.43	0.000053
E	75	V75V	gtC	gtT	12	15	B.1.177	0.000158
E	75	V75V	gtC	gtT	1	14	AY.4.5	0.000107
E	75	V75V	gtC	gtT	14	14	P.1.12	0.006776
E	75	V75V	gtC	gtT	12	12	AY.44	0.000073
E	75	V75V	gtC	gtT	9	9	B.1.427	0.000454
E	75	V75V	gtC	gtT	9	9	D.2	0.000675
E	75	V75V	gtC	gtT	2	8	AY.9	0.000135
E	75	V75V	gtC	gtT	7	7	AY.99.2	0.000645
E	75	V75V	gtC	gtT	6	6	AY.25	0.000036
E	75	V75V	gtC	gtT	6	6	AY.26	0.00017
E	75	V75V	gtC	gtT	2	6	AY.98.1	0.000097
E	75	V75V	gtC	gtT	2	5	AY.8	0.001212
E	75	V75V	gtC	gtT	5	5	B.1.429	0.000118
E	75	V75V	gtC	gtT	4	4	AY.102	0.000106
E	75	V75V	gtC	gtT	4	4	AY.114	0.000924
E	75	V75V	gtC	gtT	4	4	B.1.160	0.000125
E	75	V75V	gtC	gtT	4	4	B.1.214.1	0.08
E	75	V75V	gtC	gtT	4	4	B.1.258.17	0.000416
E	75	V75V	gtC	gtT	4	4	B.1.338	0.034483
E	75	V75V	gtC	gtT	4	4	B.1.596	0.000349
E	75	V75V	gtC	gtT	3	3		0.166667
E	75	V75V	gtC	gtT	3	3	A.28	0.007937
E	75	V75V	gtC	gtT	3	3	AY.103	0.000019
E	75	V75V	gtC	gtT	3	3	AY.29	0.000047
E	75	V75V	gtC	gtT	3	3	AY.39	0.000074
E	75	V75V	gtC	gtT	3	3	B.1.265	0.003812
E	75	V75V	gtC	gtT	3	3	B.1.335	0.030928
E	75	V75V	gtC	gtT	2	3	B.1.351	0.000059
E	75	V75V	gtC	gtT	3	3	P.1.17	0.000485
E	75	V75V	gtC	gtT	3	3	P.3	0.004785
E	75	V75V	gtC	gtT	3	3	Q.1	0.000379
E	75	V75V	gtC	gtT	2	2	AY.20	0.000078
E	75	V75V	gtC	gtT	2	2	AY.4.2	0.000043
E	75	V75V	gtC	gtT	2	2	AY.4.4	0.000818
E	75	V75V	gtC	gtT	2	2	AY.46.6	0.000144
E	75	V75V	gtC	gtT	2	2	AY.61	0.00021
E	75	V75V	gtC	gtT	2	2	AY.72	0.002721
E	75	V75V	gtC	gtT	1	2	B	0.000128
E	75	V75V	gtC	gtT	2	2	B.1.1.160	0.047619
E	75	V75V	gtC	gtT	2	2	B.1.1.318	0.000604
E	75	V75V	gtC	gtT	2	2	B.1.1.519	0.000079
E	75	V75V	gtC	gtT	1	2	B.1.177.35	0.000691
E	75	V75V	gtC	gtT	2	2	B.1.221	0.000142
E	75	V75V	gtC	gtT	2	2	B.1.234	0.000264
E	75	V75V	gtC	gtT	2	2	B.1.243	0.000139
E	75	V75V	gtC	gtT	2	2	B.1.36	0.000292
E	75	V75V	gtC	gtT	2	2	B.1.397	0.009709
E	75	V75V	gtC	gtT	2	2	B.1.416	0.002538
E	75	V75V	gtC	gtT	2	2	B.1.575	0.000607
E	75	V75V	gtC	gtT	1	2	B.1.582	0.000491
E	75	V75V	gtC	gtT	2	2	B.1.617.1	0.000258
E	75	V75V	gtC	gtT	2	2	B.1.621	0.000177
E	75	V75V	gtC	gtT	1	1	A	0.000387
E	75	V75V	gtC	gtT	1	1	AY.16.1	0.00047
E	75	V75V	gtC	gtT	1	1	AY.23	0.00007
E	75	V75V	gtC	gtT	1	1	AY.24	0.000431
E	75	V75V	gtC	gtT	1	1	AY.33	0.000067
E	75	V75V	gtC	gtT	1	1	AY.34	0.000097
E	75	V75V	gtC	gtT	1	1	AY.4.1	0.000737
E	75	V75V	gtC	gtT	1	1	AY.5	0.000021
E	75	V75V	gtC	gtT	1	1	AY.7	0.000196
E	75	V75V	gtC	gtT	1	1	AY.70	0.000209
E	75	V75V	gtC	gtT	1	1	AY.84	0.000437
E	75	V75V	gtC	gtT	1	1	AY.9.2	0.000037
E	75	V75V	gtC	gtT	1	1	AY.98	0.000079
E	75	V75V	gtC	gtT	1	1	AZ.1	0.000867
E	75	V75V	gtC	gtT	1	1	AZ.2	0.000821
E	75	V75V	gtC	gtT	1	1	B.1.1.210	0.005714
E	75	V75V	gtC	gtT	1	1	B.1.1.214	0.000055
E	75	V75V	gtC	gtT	1	1	B.1.1.25	0.000569
E	75	V75V	gtC	gtT	1	1	B.1.1.261	0.008621
E	75	V75V	gtC	gtT	1	1	B.1.1.279	0.001121
E	75	V75V	gtC	gtT	1	1	B.1.1.284	0.000107
E	75	V75V	gtC	gtT	1	1	B.1.1.46	0.004367
E	75	V75V	gtC	gtT	1	1	B.1.110	0.004525
E	75	V75V	gtC	gtT	1	1	B.1.140	0.018868
E	75	V75V	gtC	gtT	1	1	B.1.177.42	0.000894
E	75	V75V	gtC	gtT	1	1	B.1.177.54	0.000606
E	75	V75V	gtC	gtT	1	1	B.1.177.86	0.000183
E	75	V75V	gtC	gtT	1	1	B.1.232	0.000537
E	75	V75V	gtC	gtT	1	1	B.1.240	0.000216
E	75	V75V	gtC	gtT	1	1	B.1.389	0.001002
E	75	V75V	gtC	gtT	1	1	B.1.526	0.000024
E	75	V75V	gtC	gtT	1	1	B.1.541	0.004425
E	75	V75V	gtC	gtT	1	1	B.1.552	0.015152
E	75	V75V	gtC	gtT	1	1	B.1.560	0.00463
E	75	V75V	gtC	gtT	1	1	B.1.564	0.000426
E	75	V75V	gtC	gtT	1	1	B.1.637	0.000073
E	75	V75V	gtC	gtT	1	1	P.1.15	0.000232
E	75	V75V	gtC	gtT	1	1	Q.8	0.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.