CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = E : CodonNum = 65 & Codon = ctC

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
E	65	L65L		syn	ctG	ctC	3225	32	0.00992248	26437-26439

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
E	65	L65L	ctG	ctC	32	3225	All	0.000006
E	65	L65L	ctG	ctC	2	404	AY.4	0.000003
E	65	L65L	ctG	ctC	1	392	B.1.1.7	0.000001
E	65	L65L	ctG	ctC	1	313	AY.3	0.00001
E	65	L65L	ctG	ctC	3	310	B.1.617.2	0.000011
E	65	L65L	ctG	ctC	3	201	AY.44	0.000018
E	65	L65L	ctG	ctC	1	42	AY.39	0.000025
E	65	L65L	ctG	ctC	2	39	AY.25	0.000012
E	65	L65L	ctG	ctC	3	31	B.1.2	0.000026
E	65	L65L	ctG	ctC	1	19	P.1	0.000016
E	65	L65L	ctG	ctC	3	16	AY.42	0.000121
E	65	L65L	ctG	ctC	1	4	AY.3.1	0.000085
E	65	L65L	ctG	ctC	4	4	B.1.575	0.001214
E	65	L65L	ctG	ctC	1	4	B.1.621	0.000089
E	65	L65L	ctG	ctC	3	3	B.1.1.434	0.001046
E	65	L65L	ctG	ctC	1	2	AY.46.4	0.000165
E	65	L65L	ctG	ctC	1	1	B.1.1.526	0.003546
E	65	L65L	ctG	ctC	1	1	B.1.36.29	0.000517

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.